To know the role of carbondioxide partial pressure difference in central venous and arterial blood in the outcome of patients diagnosed with sepsis.
Not Applicable
- Conditions
- Health Condition 1: A00-B99- Certain infectious and parasitic diseases
- Registration Number
- CTRI/2019/05/018882
- Lead Sponsor
- Department of Anesthesiology Vardhman Mahavir Medical College and Safdarjung Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients in presence of suspected infection
2.Patients who fulfill SOFA scores >= 2
Exclusion Criteria
1.Pregnancy
2.Terminally ill patients
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess the role of pCO2 gap ( central Venous-Arterial carbon dioxide partial pressure difference )in sepsis and septic shock patients in relation to mortality and length of ICU stay <br/ ><br>Timepoint: pCO2( partial pressure of carbon dioxide) , blood lactate levels, Scvo2(central venous oxygen saturation),hemodynamic parameters, MAP(mean arterial pressure), CVP (central venous pressure) will recorded at T0 , T6 and T24 and every day.
- Secondary Outcome Measures
Name Time Method 1.To assess the role played by pCO2 gap to guide in resuscitation of septic shock patients to stabilize the hemodynamic parameters and blood lactate concentrations. <br/ ><br>2. To find the correlation between central venous-arterial pCO2 difference and ScvO2 <br/ ><br> <br/ ><br>Timepoint: pCO2(partial pressure of carbon dioxide) , blood lactate levels, Scvo2(central venous oxygen saturation),hemodynamic parameters, MAP(mean arterial pressure), CVP (central venous pressure) will recorded at T0 , T6 and T24 and every day