Manual and Expressed Placental Removal at Planned Cesarean Delivery and Its Effects on Various Cardiac Indices as Measured By Continuous Wave Doppler Ultrasonography
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 19
- 试验地点
- 2
- 主要终点
- Hemodynamic profile, especially Systemic Vascular Resistance
研究概览
简要总结
The purpose of this study is to evaluate whether manual removal of the placenta during a cesarean delivery results in higher changes in the resistance of blood flow throughout the body, also called systemic vascular resistance (SVR)
详细描述
Patients presenting to William Beaumont Hospital Royal Oak Labor and Delivery for a scheduled low transverse cesarean delivery will be asked to participate in a prospective, randomized study to evaluate any changes in systemic vascular resistance (SVR) pre- and post-delivery.
After obtaining informed consent, the patients will be randomized to one of two groups: group 1 will have manual removal of the placenta at cesarean section and group 2 will have expressed removal of the placenta at cesarean section.
Both groups will have a pre-operative continuous wave Doppler evaluation and a post-operative continuous wave Doppler evaluation at 24 hours after delivery. Continuous wave Doppler evaluation will be used pre- and post-operatively to evaluate any changes in SVR.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •scheduled for cesarean delivery
- •able to give informed consent
排除标准
- •taking medications that may affect hemodynamics
- •unable to give informed consent
研究组 & 干预措施
manual
Manual removal of placenta
干预措施: Manual removal (Behavioral)
expressed
expressed placental removal
干预措施: Expressed removal (Procedure)
结局指标
主要结局
Hemodynamic profile, especially Systemic Vascular Resistance
时间窗: immediately before and 24 hours after cesarean delivery
次要结局
- development of postpartum preeclampsia(within 1 week of delivery)
研究者
John Uckele
Attending Physician
Corewell Health East