Randomized Clinical Trial Comparing Elective Single Embryo Transfer Plus Single Embryo Cryotransfer vs Double Embryo Transfer
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 194
- 试验地点
- 2
- 主要终点
- Clinical Pregnancy Rate
研究概览
简要总结
The purpose of this study is to determine whether a policy of elective single embryo transfer (eSET) plus single embryo cryotransfer is as effective as a double embryo transfer in terms of clinical pregnancy rate
详细描述
The objective is to evaluate the In Vitro Fertilization/Intracytoplasmic Sperm Inyection (IVF/ICSI) results in terms of clinical pregnancy and multiple pregnancy rates, comparing elective single embryo transfer plus cryotransfer of one embryo if pregnancy is not achieved, with double embryo transfer.
This is a prospective randomized study, including couples arriving to the Reproductive Unit of the Hospital Universitario Virgen de las Nieves. All these patients had good reproductive prognosis and had been asigned randomly to one of the following groups: Group 1: elective single embryo transfer. In the case pregnancy is not achieved a cryotransfer of one embryo will be carried out. Group 2: elective double embryo transfer.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 37 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •women less tan 38 years
- •women Body Mass Index (BMI) between 19-39 kg/m2
- •Follicle-Stimulating Hormone (FSH) <15 mUI/mL on cycle third day
- •First IVF/ICSI cycle or second after a positive pregnancy test in the first one
排除标准
- •More tan five years of infertility
- •Previous uterus surgery
- •Uterus malformations
- •More tan one miscarriage
结局指标
主要结局
Clinical Pregnancy Rate
时间窗: Seven weeks after embryo transfer
A clinical pregnancy was defined by the presence of a gestational sac with heartbeat on transvaginal ultrasonography at the 7th weeks of pregnancy
次要结局
- Multiple Pregnancy Rate(Seven weeks after embryo transfer)
研究者
Ana Clavero Gilabert
PhD MD
University Hospital Virgen de las Nieves