Laparoscopic Bariatric Surgery: Impact of the Level of Neuromuscular Blockade on Surgical Conditions - Comparison Between Moderate and Deep Neuromuscular Blockade
Overview
- Phase
- Phase 4
- Intervention
- rocuronium
- Conditions
- Bariatric Surgery
- Sponsor
- Central Hospital, Nancy, France
- Enrollment
- 92
- Locations
- 1
- Primary Endpoint
- Improvement of surgical conditions
- Last Updated
- 10 years ago
Overview
Brief Summary
The purpose of this study is to determine whether deep neuromuscular blockade compared to moderate neuromuscular blockade may improve the surgical conditions in patients undergoing laparoscopic bariatric surgery.
Investigators
Eligibility Criteria
Inclusion Criteria
- •patient between 18 and 64 years
- •indication for bariatric surgery accordingly to HAS
- •patient undergoing laparoscopic or robotic gastric bypass surgery
- •written informed consent
- •affiliation to social security
- •Non-inclusion Criteria:
- •known hypersensibility to any of the drugs used during this study
- •absence of written informed consent
Exclusion Criteria
- Not provided
Arms & Interventions
Moderate rocuronium neuromuscular blockade
rocuronium bolus is given if needed to maintain moderate neuromuscular blockade (TOF-count 2-4) during gastrojejunal anastomosis
Intervention: rocuronium
deep rocuronium neuromuscular blockade
rocuronium bolus is given if needed to maintain deep neuromuscular blockade (here defined as a Posttetanic Count 1 - 5) during gastrojejunal anastomosis
Intervention: rocuronium
Outcomes
Primary Outcomes
Improvement of surgical conditions
Time Frame: 15 minutes
The surgical conditions will be evaluated with the King Score (M. King et al Anesthesiology 2000; 93: 1392 - 97). This score is a 4-point score. The evaluation will be done by the surgeon who is blinded. An improvement of at least 1-point will be considered as clinical relevant.
Secondary Outcomes
- Pneumoperitoneum generated pressure(15 minutes)