Chronic airway disease, mucus rheology and exacerbations: a randomized controlled trial of COPD patients (COPD-CARhE) - (COPD-CARhE)

niversity hospital of Montpellier0 个研究点目标入组 72 人开始时间: 2019年12月2日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•Between 40 and 85 years old
•Signed informed consent form
•Subjects must be able to attend all scheduled visits and comply with all testing procedures
•Beneficiary of the French social security system
•Man or woman with COPD for at least 1 year defined according to the GOLD criteria and validated by the clinical investigator
•Optimal treatment according to GOLD recommendations Grade of severity C or D
•? 1 exacerbation in the last 12 months
•Spontaneous or induced sputum production
•ECG: QTc <450 ms in man, QTc<470 ms in woman
•Normal Audiogram
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 72
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 5

•Pregnancy or breastfeeding
•Patients who are prisoners or other forms of judicial protection
•Patients under any form of tutorship / curatorship
•The patient participates in another interventional protocol, or did so in the month prior to inclusion
•Received azithromycin in the previous 3 months
•History of allergy or intolerance to macrolides / azithromycin
•Concomitant medication incompatible with azithromycin
•Other respiratory diseases or associated lung infections
•History of severe hepatic impairment (a liver function test will be performed if clinical suspicion)

发起方

niversity hospital of Montpellier