NL-OMON45755
Completed
Not Applicable
Optical Coherence Tomography to visualize neuropathology in Alzheimer's disease - OCT in AD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Alzheimer's disease and dementia
- Sponsor
- Vrije Universiteit Medisch Centrum
- Enrollment
- 120
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\- Study cases: patients with AD fulfilling the clinical criteria, a MMSE\-score of at least 17/30 and proven to be amyloid positive by either decreased CSF A\* or a positive amyloid PET scan.
- •\- Controls: patients with subjective memory complaints visiting the Alzheimer center, without diagnosis of AD or other neurodegenerative disease, proven to be amyloid negative by either normal CSF A\* or negative amyloid PET scan.
Exclusion Criteria
- •\- Subjects with neuro\-opthalmological conditions which may interfere with the OCT data
- •\- Subjects with progressive dementia, with an MMSE below 17/30 and/or incapacitated and not capable to give informed consent.
Outcomes
Primary Outcomes
Not specified
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