A prospective randomized comparative study on the Effects of Sugammadex vs Neostigmine on incidence of postoperative residual neuromuscular blockade

Rakshita Sah1 个研究点分布在 1 个国家目标入组 130 人开始时间: 2026年12月1日最近更新: 2025年11月21日

试验速览

阶段: 不适用
状态: 尚未招募
发起方
入组人数: 130
试验地点: 1

研究概览研究设计入排标准研究者研究点记录与标识符相似试验

研究概览

简要总结

Residual Neuromuscular Blockade after surgery is a prevalent yet under recognised perioperative risk which increases post operative pulmonary complications, prolongs post anesthesia care unit stay and reduces patient satisfaction. This study aims to compare sugammadex and neostigmine in typical adult surgical patients to determine if sugammadex significantly lowers RNMB incidence and improves recovery. Demonstrating such a benefit could drive practice change and enhance patient safety.

研究设计

研究类型: Interventional
分配方式: Other
盲法: Outcome Assessor Blinded

入排标准

年龄范围: 18.00 Year(s) 至 70.00 Year(s)（—）
性别: All

入选标准

•ASA Class 1-3 Elective Non cardiac, non neurologic surgery under general anesthesia with rocuronium.

排除标准

•Refusal or inability to consent.
•ASA IV or higher.
•Unstable cardiac or respiratory disease.
•BMI more than 30 kg per meter squared.
•Pregnancy or nursing.
•Emergency surgery or major protocol deviations.
•Intraoperative adverse events requiring intervention.
•Known neuromuscular disorders like myasthenia gravis Severe hepatic or renal failure.
•Allergy to study drugs History or family history of malignant hyperthermia Use of medications affecting NMB like magnesium, physostigmine.

研究者

发起方

Rakshita Sah

申办方类型

Other [self]

责任方

Principal Investigator

主要研究者

Rakshita Sah

Max Smart Super Speciality Hospital, Saket

研究点 (1)

Loading locations...

相似试验

尚未招募

不适用

Incidence of Residual Neuromuscular Blockade in the Post Anaesthesia Care Unit

CTRI/2024/09/074341Sir Ganga Ram Hospital288

招募中

不适用

Impact of Sugammadex Versus Neostigmine on Early Postoperative Pulmonary Function

NCT07309393Shanghai Pulmonary Hospital, Shanghai, China240

招募中

不适用

Deep Versus Moderate Neuromuscular Blocking

NCT07485517Menoufia University88

尚未招募

不适用

A clinical trial to study the predictive value of neuromuscular monitor-based quantitative sensory testing for postoperative pain and opioid requirement

CTRI/2026/02/104396Dayanand Medical College and Hospital53

尚未招募

不适用

A study to evaluate the rate of muscle weakness remaining after cancer surgeries.Medical and Surgical, (2) ICD-10 Condition: C00-D49||Neoplasms,

CTRI/2024/03/063717Tata Memorial Hospital300