Early Prostate cancer recurrence with PSMA PET positive unilateral pelvic lesion(s): is one-sided salvage extended lymph node dissection enough? - ProSTone Study

Martini-Klinik am UKE GmbH0 个研究点目标入组 397 人开始时间: 2019年11月29日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•Patients in good general condition with life expectancy> 10 years
•Hormone-sensitive prostate cancer recurrence after radical prostatectomy (patients with status post salvage prostatectomy may be included; salvage radiotherapy for prostate fossa and / or pelvic lymph drainage after radical prostatectomy is not an exclusion criterion)
•Unilateral detection of = 3 PSMA PET positive lymph node metastases in the pelvis (up ot origin of the inferior mesenteric artery)
•PSA at the time of PSMA PET imaging <4 ng / ml

•Contraindication for surgery or bilateral salvage lymph node dissection
•Suspected prostate cancer recurrence in the prostate fossa (local recurrence) or extrapelvic metastasis on PSMA PET imaging
•Date of PSMA PET examination > 4 months prior to salvage lymph node dissection
•Hormone therapy within 6 months prior to study enrollment

发起方