Cost-effectiveness of collaborative care for chronic medically ill patients with comorbid depressive disorder in the general hospital setting

Completed

Conditions: Depression
Major Depressive Disorder
10027946

Registration Number: NL-OMON33947

Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 150

Inclusion Criteria

All patients of the OLVG visiting the participating outpatient clinics (diabetes, cardiology, HIV, and part of lung medicine [patients with chronic obstructive pulmonary disease (COPD)]) and who already have a diagnosis specified in their file. Patients are included in the study if a cut off score of 15 (moderate to severe depressive disorder) is reached on the PHQ-9. The symptoms have to be present for at least six weeks or have to cause marked dysfunctioning (e.g. problems at work, housekeeping).

Exclusion Criteria

-Suicidal (in case of a high risk for suicide, patients will be referred.);(Concerning the following criteria a suggestion is given to the patients concerning a different kind of help:)
-Psychotic
-Suffering from dementia or delirium
-Insufficient knowledge of the Dutch language to fill in questionnaires
-Serious mental impairment
-Alcohol or drug addiction
-Already receiving psychiatric treatment
-Pregnancy
-Bipolar disorder;Concerning HIV patients:
-Organic psychosyndrome
-Personality change
-In terminal phase

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary outcome measure is remission of depressive symptoms (i.e. reduction of<br /><br>DSM-IV criteria below threshold for a depressive disorder diagnosis) as<br /><br>measured by the Dutch version of the depression subscale of the Patient Health<br /><br>Questionnaire (PHQ-9). The PHQ-9 is a brief but valid instrument that scores<br /><br>each DSM-IV criterion of a major depressive disorder. </p><br>

Secondary Outcome Measures