MedPath

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice and Pembrolizumab in Patients With Previously Untreated, Locally Advanced Inoperable or Metastatic Triple-Negative Breast Cancer

Phase 3
Active, not recruiting
Conditions
Triple Negative Breast Cancer
PD-L1 Positive
Interventions
Registration Number
NCT05382286
Lead Sponsor
Gilead Sciences
Brief Summary

The primary objective of this study is to compare the progression-free survival (PFS) between sacituzumab govitecan-hziy (SG) and pembrolizumab versus treatment of physician's choice (TPC) and pembrolizumab in participants with previously untreated, locally advanced inoperable or metastatic triple-negative breast cancer, whose tumors express programmed cell death ligand 1 (PD-L1).

Detailed Description

Not available

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
440
Inclusion Criteria
  • Individuals with locally advanced, inoperable, or metastatic triple-negative breast cancer (TNBC) who have not received previous systemic therapy for advanced disease and whose tumors are programmed cell death ligand 1 (PD-L1) positive at screening.

    • Individuals must have completed treatment for Stage I to III breast cancer, if indicated, and ≥ 6 months must have elapsed between completion of treatment with curative intent and first documented local or distant disease recurrence.
    • Individuals presenting with de novo metastatic TNBC are eligible for this study.
    • TNBC status and tumor PD-L1 combined positive score (CPS) will be confirmed centrally on a recent or archival tumor specimen.
    • Individuals must have measurable disease by computed tomography (CT) or magnetic resonance imaging (MRI) as per Response Evaluation Criteria in Solid Tumors (RECIST) Version 1.1 criteria as evaluated locally.
  • Eastern Cooperative Oncology Group (ECOG) performance status score of 0 or 1.

  • Demonstrates adequate organ function

  • Male and female individuals of childbearing potential who engage in heterosexual intercourse must agree to use protocol-specified method(s) of contraception.

  • Individuals with HIV must be on antiretroviral therapy (ART) and have a well-controlled HIV infection/disease.

Key

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Exclusion Criteria
  • Positive serum pregnancy test or women who are lactating.
  • Received prior therapy with an agent directed to another stimulatory or coinhibitory T-cell receptor.
  • Individuals may not have received systemic anticancer treatment (with the exception of endocrine therapy) within the previous 6 months or radiation therapy within 2 weeks prior to enrollment.
  • Individuals may not be participating in a study with an investigational agent or investigational device within 4 weeks prior to randomization. Individuals participating in observational studies are eligible.
  • Have previously received topoisomerase 1 inhibitors or antibody drug conjugates containing a topoisomerase inhibitor.
  • Have an active second malignancy.
  • Have active serious infection requiring antibiotics.
  • Individuals positive for HIV-1 or 2 with a history of Kaposi sarcoma and/or Multicentric Castleman Disease.
  • Have active hepatitis B virus (HBV) or hepatitis C virus (HCV) infection.
  • Has an active autoimmune disease that has required systemic treatment in the past 2 years.

Note: Other protocol defined Inclusion/Exclusion criteria may apply.

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Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Pembrolizumab + Treatment of Physician's Choice (TPC)PaclitaxelParticipants will receive pembrolizumab 200 mg on Day 1 of each 21-day cycle (maximum 35 cycles) plus TPC determined prior to randomization from 1 of the 3 allowed regimens: * Paclitaxel 90 mg/m\^2 on Days 1, 8, and 15 of 28-day cycles * nab-Paclitaxel 100 mg/m\^2 on Days 1, 8, and 15 of 28-day cycles * Gemcitabine 1000 mg/m\^2 + carboplatin area under the curve (AUC) 2 on Days 1 and 8 of 21-day cycles
Pembrolizumab + Treatment of Physician's Choice (TPC)nab-PaclitaxelParticipants will receive pembrolizumab 200 mg on Day 1 of each 21-day cycle (maximum 35 cycles) plus TPC determined prior to randomization from 1 of the 3 allowed regimens: * Paclitaxel 90 mg/m\^2 on Days 1, 8, and 15 of 28-day cycles * nab-Paclitaxel 100 mg/m\^2 on Days 1, 8, and 15 of 28-day cycles * Gemcitabine 1000 mg/m\^2 + carboplatin area under the curve (AUC) 2 on Days 1 and 8 of 21-day cycles
Sacituzumab Govitecan-hziy (SG) + PembrolizumabSacituzumab Govitecan-hziyParticipants will receive SG 10 mg/kg on Days 1 and 8 of 21-day cycles and pembrolizumab 200 mg on Day 1 of 21-day cycles Pembrolizumab will be administered for a maximum of 35 cycles.
Pembrolizumab + Treatment of Physician's Choice (TPC)PembrolizumabParticipants will receive pembrolizumab 200 mg on Day 1 of each 21-day cycle (maximum 35 cycles) plus TPC determined prior to randomization from 1 of the 3 allowed regimens: * Paclitaxel 90 mg/m\^2 on Days 1, 8, and 15 of 28-day cycles * nab-Paclitaxel 100 mg/m\^2 on Days 1, 8, and 15 of 28-day cycles * Gemcitabine 1000 mg/m\^2 + carboplatin area under the curve (AUC) 2 on Days 1 and 8 of 21-day cycles
Sacituzumab Govitecan-hziy (SG) + PembrolizumabPembrolizumabParticipants will receive SG 10 mg/kg on Days 1 and 8 of 21-day cycles and pembrolizumab 200 mg on Day 1 of 21-day cycles Pembrolizumab will be administered for a maximum of 35 cycles.
Pembrolizumab + Treatment of Physician's Choice (TPC)CarboplatinParticipants will receive pembrolizumab 200 mg on Day 1 of each 21-day cycle (maximum 35 cycles) plus TPC determined prior to randomization from 1 of the 3 allowed regimens: * Paclitaxel 90 mg/m\^2 on Days 1, 8, and 15 of 28-day cycles * nab-Paclitaxel 100 mg/m\^2 on Days 1, 8, and 15 of 28-day cycles * Gemcitabine 1000 mg/m\^2 + carboplatin area under the curve (AUC) 2 on Days 1 and 8 of 21-day cycles
Pembrolizumab + Treatment of Physician's Choice (TPC)GemcitabineParticipants will receive pembrolizumab 200 mg on Day 1 of each 21-day cycle (maximum 35 cycles) plus TPC determined prior to randomization from 1 of the 3 allowed regimens: * Paclitaxel 90 mg/m\^2 on Days 1, 8, and 15 of 28-day cycles * nab-Paclitaxel 100 mg/m\^2 on Days 1, 8, and 15 of 28-day cycles * Gemcitabine 1000 mg/m\^2 + carboplatin area under the curve (AUC) 2 on Days 1 and 8 of 21-day cycles
Primary Outcome Measures
NameTimeMethod
Progression-free Survival (PFS) as Assessed by Blinded Independent Central Review (BICR) per Response Evaluation Criteria in Solid Tumors (RECIST) Version 1.1Randomization up to approximately 33 months

PFS is defined as the time from the date of randomization until the date of objective progressive disease (PD) or death (whichever comes first).

Secondary Outcome Measures
NameTimeMethod
Percentage of Participants Experiencing Treatment-emergent Adverse Events (TEAEs)First dose date up to 53 months plus 30 days
Overall Survival (OS)Randomization up to approximately 53 months

OS is defined as the time from the date of randomization until death due to any cause.

Time to Response (TTR) as Assessed by BICR per RECIST Version 1.1Randomization up to approximately 53 months

TTR is defined as the time from the date of randomization until the first documentation of CR or PR.

Objective Response Rate (ORR) as Assessed by BICR per RECIST Version 1.1Randomization up to approximately 53 months

ORR is defined as the proportion of participants who achieve complete response (CR) or partial response (PR) that is confirmed at least 4 weeks after initial documentation of response.

Percentage of Participants Experiencing Clinical Laboratory AbnormalitiesFirst dose date up to 53 months plus 30 days
Time to Deterioration (TTD) in Global Health Status/Quality of Life (QoL) Scale as Measured by the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire, Core Questionnaire, Version 3.0 (EORTC QLQ-C30)Randomization up to approximately 53 months

The EORTC QLQ-C30 is a questionnaire to assess quality of life of cancer patients, it is composed of 30 questions (items) resulting in 5 functional scales, 1 global health status scale, 3 symptom scales, and 6 single items. Scoring of the QLQ-C30 is performed according to QLQ-C30 Scoring manual. All of the scales and single-item measures range in score from 0 to 100. Higher score for the functioning scales and global health status denote a better level of functioning (i.e. a better state of the participant), while higher scores on the symptom and single-item scales indicate a higher level of symptoms (i.e. a worse state of the participant).

TTD of Pain Score as Measured by EORTC QLQ-C30Randomization up to approximately 53 months

The EORTC QLQ-C30 is a questionnaire to assess quality of life of cancer patients, it is composed of 30 questions (items) resulting in 5 functional scales, 1 global health status scale, 3 symptom scales, and 6 single items. Scoring of the QLQ-C30 is performed according to QLQ-C30 Scoring manual. All of the scales and single-item measures range in score from 0 to 100. Higher score for the functioning scales and global health status denote a better level of functioning (i.e. a better state of the participant), while higher scores on the symptom and single-item scales indicate a higher level of symptoms (i.e. a worse state of the participant).

TTD of Role Functioning Score as Measured by EORTC QLQ-C30Randomization up to approximately 53 months

The EORTC QLQ-C30 is a questionnaire to assess quality of life of cancer patients, it is composed of 30 questions (items) resulting in 5 functional scales, 1 global health status scale, 3 symptom scales, and 6 single items. Scoring of the QLQ-C30 is performed according to QLQ-C30 Scoring manual. All of the scales and single-item measures range in score from 0 to 100. Higher score for the functioning scales and global health status denote a better level of functioning (ie, a better state of the participant), while higher scores on the symptom and single-item scales indicate a higher level of symptoms (ie, a worse state of the participant).

Duration of Response (DOR) as Assessed by BICR per RECIST Version 1.1Randomization up to approximately 53 months

DOR is defined as the time from the first documentation of CR or PR to the earlier of the first documentation of objective PD or death from any cause (whichever comes first).

TTD of Fatigue Score as Measured by EORTC QLQ-C30Randomization up to approximately 53 months

The EORTC QLQ-C30 is a questionnaire to assess quality of life of cancer patients, it is composed of 30 questions (items) resulting in 5 functional scales, 1 global health status scale, 3 symptom scales, and 6 single items. Scoring of the QLQ-C30 is performed according to QLQ-C30 Scoring manual. All of the scales and single-item measures range in score from 0 to 100. Higher score for the functioning scales and global health status denote a better level of functioning (ie, a better state of the participant), while higher scores on the symptom and single-item scales indicate a higher level of symptoms (ie, a worse state of the participant).

TTD of Physical Functioning Domain Score as Measured by EORTC QLQ-C30Randomization up to approximately 53 months

The EORTC QLQ-C30 is a questionnaire to assess quality of life of cancer patients, it is composed of 30 questions (items) resulting in 5 functional scales, 1 global health status scale, 3 symptom scales, and 6 single items. Scoring of the QLQ-C30 is performed according to QLQ-C30 Scoring manual. All of the scales and single-item measures range in score from 0 to 100. Higher score for the functioning scales and global health status denote a better level of functioning (ie, a better state of the participant), while higher scores on the symptom and single-item scales indicate a higher level of symptoms (ie, a worse state of the participant).

Trial Locations

Locations (504)

University of Pennsylvania Abramson Cancer Center

🇺🇸

Philadelphia, Pennsylvania, United States

Magee-Womens Hospital of UPMC

🇺🇸

Pittsburgh, Pennsylvania, United States

Magee-Womens Hospital of UPMC,5115 Centre Avenue

🇺🇸

Pittsburgh, Pennsylvania, United States

Magee-Womens Hospital of UPMC,9100 Babcock Boulevard

🇺🇸

Pittsburgh, Pennsylvania, United States

Magee-Womens Hospital of UPMC,100 Fairfield Dr

🇺🇸

Seneca, Pennsylvania, United States

Magee-Womens Hospital of UPMC,470 Johnson Road

🇺🇸

Washington, Pennsylvania, United States

Magee-Womens Hospital of UPMC,1703 Innovation Drive

🇺🇸

York, Pennsylvania, United States

Rhode Island Hospital

🇺🇸

Providence, Rhode Island, United States

Rhode Island Hospital,164 Summit Ave, Fain 275A

🇺🇸

Providence, Rhode Island, United States

Tennessee Oncology, PLLC,103 Natchez Park Drive

🇺🇸

Dickson, Tennessee, United States

Tennessee Oncology, PLLC,4488 Carothers Parkway

🇺🇸

Franklin, Tennessee, United States

Tennessee Oncology, PLLC,225 Big Station Camp Blvd

🇺🇸

Gallatin, Tennessee, United States

The West Clinic, PLLC dba West Cancer Center

🇺🇸

Germantown, Tennessee, United States

Tennessee Oncology, PLLC,353 New Shackle Island Road

🇺🇸

Hendersonville, Tennessee, United States

Tennessee Oncology, PLLC,5653 First Blvd.

🇺🇸

Hermitage, Tennessee, United States

Tennessee Oncology, PLLC,103 Physicians Way

🇺🇸

Lebanon, Tennessee, United States

Tennessee Oncology, PLLC,1840 Medical Center Parkway

🇺🇸

Murfreesboro, Tennessee, United States

Tennessee Oncology, PLLC,2004 Hayes Street

🇺🇸

Nashville, Tennessee, United States

Tennessee Oncology, PLLC,SCRI Oncology Partners

🇺🇸

Nashville, Tennessee, United States

Tennessee Oncology, PLLC

🇺🇸

Nashville, Tennessee, United States

Tennessee Oncology, PLLC,4220 Harding Rd

🇺🇸

Nashville, Tennessee, United States

Tennessee Oncology, PLLC,3443 Dickerson Road

🇺🇸

Nashville, Tennessee, United States

Tennessee Oncology, PLLC,397 Wallace Road

🇺🇸

Nashville, Tennessee, United States

Tennessee Oncology, PLLC,120 Frank Martin Road

🇺🇸

Shelbyville, Tennessee, United States

Tennessee Oncology, PLLC,300 Stonecrest Blvd

🇺🇸

Smyrna, Tennessee, United States

The Center for Cancer and Blood Disorders - Magnolia,515 W. Mayfield Rd.

🇺🇸

Arlington, Texas, United States

Texas Oncology-Austin,901 West 38th Street

🇺🇸

Austin, Texas, United States

Texas Oncology-Austin

🇺🇸

Austin, Texas, United States

Texas Oncology-Austin,4101 James Casey, Suite 100

🇺🇸

Austin, Texas, United States

The Center for Cancer and Blood Disorders - Magnolia,11805 South Freeway

🇺🇸

Burleson, Texas, United States

Texas Oncology-Baylor Charles A. Sammons Cancer Center

🇺🇸

Dallas, Texas, United States

Texas Oncology-Denison

🇺🇸

Denison, Texas, United States

The Center for Cancer and Blood Disorders - Magnolia

🇺🇸

Fort Worth, Texas, United States

Oncology Consultants,1631 North Loop West

🇺🇸

Houston, Texas, United States

Oncology Consultants,925 Gessner

🇺🇸

Houston, Texas, United States

Oncology Consultants

🇺🇸

Houston, Texas, United States

University of Texas MD Anderson Cancer Center,1155 Pressler St

🇺🇸

Houston, Texas, United States

University of Texas MD Anderson Cancer Center

🇺🇸

Houston, Texas, United States

Mays Cancer Center

🇺🇸

San Antonio, Texas, United States

The Center for Cancer and Blood Disorders - Magnolia,920 Santa Fe Drive

🇺🇸

Weatherford, Texas, United States

Huntsman Cancer Institute, University of Utah,165 North University Avenue

🇺🇸

Farmington, Utah, United States

Huntsman Cancer Institute, University of Utah,1280 E. Stringham Avenue

🇺🇸

Salt Lake City, Utah, United States

Huntsman Cancer Institute, University of Utah

🇺🇸

Salt Lake City, Utah, United States

Huntsman Cancer Institute, University of Utah,5126 West Daybreak Parkway

🇺🇸

South Jordan, Utah, United States

Virginia Oncology Associates,744 N. Battlefield Blvd

🇺🇸

Chesapeake, Virginia, United States

Virginia Cancer Institute,7501 Right Flank Road

🇺🇸

Mechanicsville, Virginia, United States

Virginia Oncology Associates,1051 Loftis Blvd Suite 100

🇺🇸

Newport News, Virginia, United States

Virginia Oncology Associates

🇺🇸

Norfolk, Virginia, United States

Virginia Cancer Institute,210 Medical Park Boulevard

🇺🇸

Petersburg, Virginia, United States

Virginia Cancer Institute,1401 Johnston-Willis Drive

🇺🇸

Richmond, Virginia, United States

Virginia Cancer Institute

🇺🇸

Richmond, Virginia, United States

Virginia Oncology Associates,1950 Glenn Mitchell Drive

🇺🇸

Virginia Beach, Virginia, United States

Northwest Cancer Specialists, PC,210 SE 136th Avenue

🇺🇸

Vancouver, Washington, United States

Hospital Británico de Buenos Aires

🇦🇷

Buenos Aires, Argentina

Instituto de Oncología Ángel H. Roffo

🇦🇷

Caba, Argentina

Fundacion CORI para la Investigacioy y Prevención del Cancer

🇦🇷

Capital, Argentina

Instituto de Oncologia de Rosario

🇦🇷

Rosario, Argentina

CAIPO Centro Para La Atención Integral Del Pacient

🇦🇷

San Miguel de Tucumán, Argentina

Clinica Viedma

🇦🇷

Viedma, Argentina

Border Medical Oncology

🇦🇺

Albury, New South Wales, Australia

Saint George Hospital - Australia

🇦🇺

Kogarah, New South Wales, Australia

Mater Hospital - North Sydney

🇦🇺

North Sydney, New South Wales, Australia

GenesisCare - North Shore

🇦🇺

St Leonards, New South Wales, Australia

Mater Misericordiae Limited and Mater Research Limited

🇦🇺

South Brisbane, Queensland, Australia

Princess Alexandra Hospital

🇦🇺

Woolloongabba, Queensland, Australia

Cancer Research SA (CRSA)

🇦🇺

Adelaide, South Australia, Australia

Icon Cancer Centre Hobart

🇦🇺

Hobart, Tasmania, Australia

Monash Medical Centre

🇦🇺

Clayton, Victoria, Australia

Austin Hospital

🇦🇺

Melbourne, Victoria, Australia

Peter MacCallum Cancer Centre

🇦🇺

Parkville, Victoria, Australia

Breast Cancer Research Center - Western Australia

🇦🇺

Nedlands, Western Australia, Australia

Medizinische Universität Innsbruck

🇦🇹

Innsbruck, Austria

Ordensklinikum Linz GmbH Barmherzige Schwestern

🇦🇹

Linz, Austria

Landeskrankenhaus Salzburg

🇦🇹

Salzburg, Austria

Universitätsklinikum Sankt Pölten

🇦🇹

Sankt Poelten, Austria

Medizinische Universität Wien

🇦🇹

Wien, Austria

Institut Jules Bordet

🇧🇪

Anderlecht, Belgium

Algemeen Ziekenhuis Klina

🇧🇪

Brasschaat, Belgium

Cliniques Universitaires Saint-Luc

🇧🇪

Brussels, Belgium

Universitair Ziekenhuis Brussel

🇧🇪

Brussels, Belgium

Grand Hopital de Charleroi - Notre Dame

🇧🇪

Charleroi, Belgium

Universitair Ziekenhuis Gent

🇧🇪

Gent, Belgium

UZ Leuven

🇧🇪

Leuven, Belgium

Centre Hospitalier Universitaire Université Cathol

🇧🇪

Namur, Belgium

Hospital Araújo Jorge - Associacao de Combate ao Cancer em Goias - ACCG

🇧🇷

Goiânia, Brazil

Centro de Pesquisa Clinica Em Oncologia - ONCOSITE

🇧🇷

Ijui, Brazil

Hospital de Clinicas de Porto Alegre - HCPA

🇧🇷

Itajai, Brazil

Centro de Pesquisas Clinicas da Fundacao Doutor Amaral Carvalho - Hospital Amarval Carvalho

🇧🇷

Jau, Brazil

Associacao Hosptialar Moinos de Vento - Hospital Moinhos de Vento

🇧🇷

Porto Alegre, Brazil

Hospital de Clínicas de Porto Alegre

🇧🇷

Porto Alegre, Brazil

Hospital Sao Lucas da PUCRS

🇧🇷

Porto Alegre, Brazil

Instituto Nacional de Câncer - Brazil

🇧🇷

Rio de Janeiro, Brazil

Núcleo de Oncologia da Bahia

🇧🇷

Salvador, Brazil

CEPHO - Centro de Estudos e Pesquisas de Hematologia e Oncologia - Centro Universitário FMABC

🇧🇷

Santo Andre, Brazil

Real e Benemerita Associacao Portuguesa de Beneficencia - Hospital Beneficencia Portuguesa (BP) - Unidade Paulista

🇧🇷

São Paulo, Brazil

Clinica de Pesquisas e Centro de Estudos em Oncolo

🇧🇷

São Paulo, Brazil

Fundação Pio XII - Hospital de Câncer de Barretos

🇧🇷

São Paulo, Brazil

Nucleo de Pesquisa Clinica da Rede Sao Camilo

🇧🇷

São Paulo, Brazil

Tom Baker Cancer Centre

🇨🇦

Calgary, Canada

Cross Cancer Institute

🇨🇦

Edmonton, Canada

QEII Health Sciences Centre

🇨🇦

Halifax, Canada

Grand River Regional Cancer Centre at Grand River Hospital

🇨🇦

Kitchener, Canada

London Health Sciences Centre

🇨🇦

London, Canada

McGill University Health Centre

🇨🇦

Montreal, Canada

Jewish General Hospital

🇨🇦

Montréal, Canada

Princess Margaret Cancer Centre - University Health Network

🇨🇦

Ontario, Canada

Ottawa Hospital - General Campus

🇨🇦

Ottawa, Canada

Sunnybrook Research Institute

🇨🇦

Toronto, Canada

Mount Sinai Hospital

🇨🇦

Toronto, Canada

British Columbia Cancer - Vancouver

🇨🇦

Vancouver, Canada

Oncovida - Santiago

🇨🇱

Providencia, Chile

Clínica IRAM

🇨🇱

Santiago DE CHILE, Chile

Centro de Cancer Pontificia Universidad Catolica

🇨🇱

Santiago Region, Chile

Clínica Alemana

🇨🇱

Santiago, Chile

James Lind Centro de Investigacion del Cancer

🇨🇱

Temuco, Chile

Masarykuv Onkologicky Ustav, Klinika Komplexni Onkologicke Pece

🇨🇿

Brno, Czechia

Fakultní Thomayerova nemocnice

🇨🇿

Hradec Kralove, Czechia

Fakultní Nemocnice Hradec Králové

🇨🇿

Hradec Králové, Czechia

Fakultni nemocnice Olomouc, Onkologicka klinika

🇨🇿

Olomouc, Czechia

Vseobecna Fakultni Nemocnice v Praze, Onkologicka klinika

🇨🇿

Prague, Czechia

Fakultní Nemocnice Královské Vinohrady, Radioterapeuticka a onkologicka klinika

🇨🇿

Praha, Czechia

Sainte Catherine Institut du Cancer Avignon Provence

🇫🇷

Avignon, France

Centre Hospitalier Régional et Universitaire de Be

🇫🇷

Besancon, France

Polyclinique Bordeaux Nord Aquitaine

🇫🇷

Bordeaux, France

Hôpital Morvan, Institut de cancérologie

🇫🇷

Brest, France

Centre de Lutte contre le Cancer - François Bacles

🇫🇷

Caen, France

Centre Jean Perrin

🇫🇷

Clermont Ferrand, France

Centre Leon Berard

🇫🇷

Lyon, France

Institut Paoli-Calmettes

🇫🇷

Marseille CEDEX 9, France

Institut Régional du Cancer de Montpellier

🇫🇷

Montpellier Cedex 5, France

Centre Eugène Marquis

🇫🇷

Rennes Cedex, France

Institut Claudius Regaud - IUCT-O

🇫🇷

Toulouse, France

Centre de Cancérologie du Grand Montpellier

🇫🇷

Montpellier, France

Hôpital Privé du Confluent

🇫🇷

Nantes, France

Hospices Civils de Lyon, Hôpital Lyon Sud

🇫🇷

Pierre-Benite, France

Centre Armoricain de Radiothérapie, dImagerie Méd

🇫🇷

Plerin, France

Institut Gustave Roussy

🇫🇷

Villejuif, France

Helios Klinikum Berlin-Buch

🇩🇪

Berlin, Germany

: Gynakologisches Zentrum Bonn, Schwerpunkt Gyn. Onkologie,

🇩🇪

Bonn, Germany

Marienhospital Bottrop

🇩🇪

Bottrop, Germany

Universitätsklinikum Erlangen, Frauen klinik

🇩🇪

Erlangen, Germany

Kliniken Essen-Mitte - Evangelische Huyssens-Stift

🇩🇪

Essen, Germany

Praxis für interdisziplinäre Onkologie & Hämatolog

🇩🇪

Freiburg, Germany

: Universitätsklinikum Hamburg-Eppendorf

🇩🇪

Hamburg, Germany

Facharztzentrum Eppendorf

🇩🇪

Hamburg, Germany

Nationales Centrum für Tumorerkrankungen

🇩🇪

Heidelberg, Germany

Universitätsklinikum Schleswig-Holstein Institut fur Klinische Chermie

🇩🇪

Lübeck, Germany

Klinik Frauenheilkunde, Uniklinik ClO, Studienzentrale

🇩🇪

Köln, Germany

Universitatsklinikum Mannheim GmBH, Frauenklinik

🇩🇪

Mannheim, Germany

Universitätsklinikum Münster, Bereich Senologie an der klinik fur Frauenheilkunde und Gerburtschilfe

🇩🇪

Munster, Germany

EV. Krankenhaus Bethesda - Johanniter GmbH, Station 1 Brustzentrum Niederrhein

🇩🇪

Mönchengladbach, Germany

Rotkreuzklinikum Munchen Frauenklinik

🇩🇪

München, Germany

Klinik und Poliklinik für Frauenheilkunde

🇩🇪

München, Germany

Universitatsklinikum Tubingen

🇩🇪

Tübingen, Germany

St. Josefs-Hospital Wiesbaden GmbH, Gynakologie und Geburtshilfe

🇩🇪

Wiesbaden, Germany

Department of Medicine, Queen Mary Hospital

🇭🇰

Hong Kong, Hong Kong

Hong Kong Sanatorium and Hospital

🇭🇰

Hong Kong, Hong Kong

Tuen Mun Hospital

🇭🇰

Hong Kong, Hong Kong

Prince of Wales Hospital - Hong Kong

🇭🇰

New Territories, Hong Kong

Orszagos Onkologiai Intezet

🇭🇺

Budapest, Hungary

Uzsoki Utcai Kórház

🇭🇺

Budapest, Hungary

Debreceni Egyetem Klinikai Központ

🇭🇺

Debrecen, Hungary

Rambam Health Care Campus

🇮🇱

Haifa, Israel

Shaare Zedek Medical Center

🇮🇱

Jerusalem, Israel

Petz Aladár Egyetemi Oktató Kórház - Gy?r

🇭🇺

Gyor, Hungary

Soroka Medical Center

🇮🇱

Beer-Sheva, Israel

Hadassah - Hebrew University Medical Center

🇮🇱

Jerusalem, Israel

Meir Medical Center

🇮🇱

Kfar Saba, Israel

Rabin Medical Center

🇮🇱

Petah Tikva, Israel

Kaplan Medical Center

🇮🇱

Rehovot, Israel

Sheba Medical Center Hospital - Tel Hashomer

🇮🇱

Tel Aviv, Israel

Tel Aviv Sourasky Medical Center

🇮🇱

Tel Aviv, Israel

SSD Oncologia Medica Addarii-Zamagni, IRCSS Azienda Ospedaliero-Universitaria di Bologna - Policlinico di Sant'Orsola

🇮🇹

Bologna, Italy

UO Oncologia, ASST degli Spedali Civili di Brescia

🇮🇹

Brescia, Italy

IRCCS Ospedale Policlinico San Martino

🇮🇹

Genova GE, Italy

IRCCS Istituto Tumori "Giovanni Paolo II"

🇮🇹

Bari, Italy

S.C. Oncologia medica, ASST di Lecco

🇮🇹

Lecco, Italy

Presidio Ospedaliero di Lucca

🇮🇹

Lucca, Italy

Ospedale Generale Provinciale - Macerata

🇮🇹

Macerata, Italy

Ospedale San Raffaele

🇮🇹

Milano, Italy

Fondazione IRCCS - Istituto Nazionale dei Tumori

🇮🇹

Milano, Italy

Istituto Europeo di Oncologia

🇮🇹

Milan, Italy

Centro Ricerca Fase I, Fondazione IRCSS San Gerado dei Tintori

🇮🇹

Monza, Italy

AOU "Luigi Vanvitelli"

🇮🇹

Napoli, Italy

Oncologia Medica Senologica Sperimentale - Istituto Nazionale Tumori IRCCS Fondazione G. Pascale

🇮🇹

Napoli, Italy

AOU Maggiore della Carita

🇮🇹

Novara, Italy

Istituto Oncologico Veneto - IRCCS

🇮🇹

Padova, Italy

S.O.C Oncologia Medica, Nuovo Ospedale di Prato Santo Stefano

🇮🇹

Prato, Italy

Policlinico di Roma

🇮🇹

Roma, Italy

Fondazione Policlinico Universitario Agostino Geme

🇮🇹

Rome, Italy

Azienda Ospedaliera Universitaria Senese - Losped

🇮🇹

Siena, Italy

Aichi Cancer Center Hospital

🇯🇵

Aichi, Japan

Tohoku University Hospital

🇯🇵

Aoba-ku, Japan

Magee-Womens Hospital of UPMC,300 Halket Street

🇺🇸

Pittsburgh, Pennsylvania, United States

Alaska Oncology and Hematology

🇺🇸

Anchorage, Alaska, United States

Arizona Oncology Associates, PC-Hope,1845 W Orange Grove Rd

🇺🇸

Tucson, Arizona, United States

Arizona Oncology Associates, PC-Hope,2070 W. Rudasill Rd.

🇺🇸

Tucson, Arizona, United States

Arizona Oncology Associates, PC-Hope

🇺🇸

Tucson, Arizona, United States

Arizona Oncology Associates, PC-Hope,1620 West St. Mary's Road

🇺🇸

Tucson, Arizona, United States

Genesis Cancer and Blood Institute

🇺🇸

Hot Springs, Arkansas, United States

Genesis Cancer and Blood Institute,1456 Higdon Ferry Road Suite B.

🇺🇸

Hot Springs, Arkansas, United States

Saint Bernards Medical Center

🇺🇸

Jonesboro, Arkansas, United States

Saint Bernards Medical Center,4000 Linwood Drive

🇺🇸

Paragould, Arkansas, United States

Chiba Cancer Center

🇯🇵

Chuo-ku, Japan

Osaka Prefectural Hospital Organization Osaka International Cancer Institute

🇯🇵

Chuo-ku, Japan

NHO Shikoku Cancer Center

🇯🇵

Ehime, Japan

Fukushima Medical University Hospital

🇯🇵

Fukushima, Japan

Saitama Cancer Center

🇯🇵

Inamachi, Japan

Hakuaikai Sagara Hospital

🇯🇵

Kagoshima-shi, Japan

Juntendo University Hospital

🇯🇵

Bunkyo-ku, Japan

Tokai University Hospital

🇯🇵

Kanagawa, Japan

National Cancer Center Hospital East

🇯🇵

Kashiwa, Japan

The Cancer Institute Hospital of JFCR

🇯🇵

Koto-ku, Japan

Rocky Mountain Cancer Centers,2312 N. Nevada Avenue

🇺🇸

Colorado Springs, Colorado, United States

Rocky Mountain Cancer Centers,6031 E. Woodman Rd.

🇺🇸

Colorado Springs, Colorado, United States

Rocky Mountain Cancer Centers,4700 E. Hale Parkway

🇺🇸

Denver, Colorado, United States

Rocky Mountain Cancer Centers,11750 West 2nd Place

🇺🇸

Lakewood, Colorado, United States

Rocky Mountain Cancer Centers,22 West Dry Creek Circle

🇺🇸

Littleton, Colorado, United States

Rocky Mountain Cancer Centers,10107 Ridge Gate Parkway

🇺🇸

Lone Tree, Colorado, United States

Rocky Mountain Cancer Centers,2030 Mountain View Ave Ste 210

🇺🇸

Longmont, Colorado, United States

Rocky Mountain Cancer Centers,3676 Parker Blvd

🇺🇸

Pueblo, Colorado, United States

Kumamoto University Hospital

🇯🇵

Kumamoto- shi, Japan

Kure Medical Center And Chugoku Cancer Center

🇯🇵

Kure, Japan

Mie University Hospital

🇯🇵

Mie, Japan

Nagoya University Hospital

🇯🇵

Nagoya, Japan

Rocky Mountain Cancer Centers,525 W. 15th Street

🇺🇸

Pueblo, Colorado, United States

Rocky Mountain Cancer Centers,8820 Huron Street

🇺🇸

Thornton, Colorado, United States

Eastern Connecticut Hematology and Oncology Associates

🇺🇸

Norwich, Connecticut, United States

Advent Health Medical Group

🇺🇸

Altamonte Springs, Florida, United States

Nagoya City University Hospital

🇯🇵

Nagoya, Japan

Hiroshima City Hiroshima Citizens Hospital

🇯🇵

Naka-ku, Japan

NIigata Cancer Center Hospital

🇯🇵

Niigata-shi, Japan

Okayama University Hospital

🇯🇵

Okayama, Japan

Gunma Prefectural Cancer Center

🇯🇵

Ota, Japan

Kyoto University Hospital

🇯🇵

Sakyo-ku, Japan

Hokkaido Cancer Center

🇯🇵

Sapporo, Japan

SCRI - Florida Cancer Specialists - North Region R,750 Orienta Ave

🇺🇸

Altamonte Springs, Florida, United States

University of Miami - Sylvester Comprehensive Cancer Center,2801 NE 213th St

🇺🇸

Aventura, Florida, United States

Shizuoka General Hospital

🇯🇵

Shizuoka-city, Japan

Florida Cancer Specialists,9776 Bonita Beach Road Southeast Suite 201 A

🇺🇸

Bonita Springs, Florida, United States

Florida Cancer Specialists,3630 Manatee Avenue West

🇺🇸

Bradenton, Florida, United States

Florida Cancer Specialists,5985 Silver Falls Run

🇺🇸

Bradenton, Florida, United States

Shizuoka Cancer Center

🇯🇵

Shizuoka, Japan

Osaka University Hospital

🇯🇵

Suita, Japan

Showa University Hospital

🇯🇵

Tokyo, Japan

SCRI - Florida Cancer Specialists - North Region R,403 S. Kings Ave.

🇺🇸

Brandon, Florida, United States

Florida Cancer Specialists,1030 Commerce Creek Blvd

🇺🇸

Cape Coral, Florida, United States

SCRI - Florida Cancer Specialists - North Region R,3280 McMullen Booth Road

🇺🇸

Clearwater, Florida, United States

University of Miami - Sylvester Comprehensive Cancer Center,5555 Ponce De Leon Blvd

🇺🇸

Coral Gables, Florida, United States

SCRI - Florida Cancer Specialists - West Palm Beach,224 Memorial Medical Parkway, Suite 300

🇺🇸

Daytona Beach, Florida, United States

Kanagawa Cancer Center

🇯🇵

Yokohama, Japan

SCRI - Florida Cancer Specialists - North Region R,3402 West Dr. Martin Luther King Jr. Boulevard

🇺🇸

Tampa, Florida, United States

SCRI - Florida Cancer Specialists - North Region R,4100 Waterman Way

🇺🇸

Tavares, Florida, United States

SCRI - Florida Cancer Specialists - North Region R,1400 US Highway 441 N

🇺🇸

The Villages, Florida, United States

SCRI - Florida Cancer Specialists - North Region R,9320 State Road 54

🇺🇸

Trinity, Florida, United States

Florida Cancer Specialists,836 Sunset Lake Blvd

🇺🇸

Venice, Florida, United States

SCRI - Florida Cancer Specialists - West Palm Beach,3730 7th Terrace, Suite 101

🇺🇸

Vero Beach, Florida, United States

SCRI - Florida Cancer Specialists - West Palm Beach,1037 S. State Road 7, Bldg B, Suite 303

🇺🇸

Wellington, Florida, United States

SCRI - Florida Cancer Specialists - West Palm Beach

🇺🇸

West Palm Beach, Florida, United States

SCRI - Florida Cancer Specialists - North Region R,460 N Orlando Ave

🇺🇸

Winter Park, Florida, United States

Northside Hospital,125 King Avenue

🇺🇸

Athens, Georgia, United States

Piedmont Cancer Institute - Atlanta,1267 Hwy 54W

🇺🇸

Atlanta, Georgia, United States

Winship Cancer Institute of Emory University,550 Peachtree St NE

🇺🇸

Atlanta, Georgia, United States

Piedmont Cancer Institute - Atlanta

🇺🇸

Atlanta, Georgia, United States

National Cancer Center - Korea

🇰🇷

Goyang-si Gyeonggi-do, Korea, Republic of

The University of Kansas Cancer Center,12200 W. 110th Street

🇺🇸

Overland Park, Kansas, United States

The University of Kansas Cancer Center,10710 Nall Avenue

🇺🇸

Overland Park, Kansas, United States

The University of Kansas Cancer Center,10730 Nall Avenue

🇺🇸

Overland Park, Kansas, United States

The University of Kansas Cancer Center

🇺🇸

Westwood, Kansas, United States

Norton Cancer Institute - Saint Matthews,234 E. Gray Strret

🇺🇸

Louisville, Kentucky, United States

Norton Cancer Institute - Saint Matthews,676 S. Floyd Street

🇺🇸

Louisville, Kentucky, United States

Norton Cancer Institute - Saint Matthews

🇺🇸

Louisville, Kentucky, United States

Norton Cancer Institute - Saint Matthews,4955 Norton Healthcare Blvd

🇺🇸

Louisville, Kentucky, United States

Hematology Oncology Clinic - Baton Rouge

🇺🇸

Baton Rouge, Louisiana, United States

Hematology Oncology Clinic - Baton Rouge,1673 E Mount Please Drive

🇺🇸

Zachary, Louisiana, United States

Cancer Institute Ascension Saint Agnes

🇺🇸

Baltimore, Maryland, United States

Beth Israel Deaconess Medical Center

🇺🇸

Boston, Massachusetts, United States

Dana-Farber Cancer Institute

🇺🇸

Boston, Massachusetts, United States

Massachusetts General Hospital

🇺🇸

Boston, Massachusetts, United States

Massachusetts General Hospital,102 Endicott Street

🇺🇸

Danvers, Massachusetts, United States

Massachusetts General Hospital,2014 Washington St

🇺🇸

Newton, Massachusetts, United States

University of Michigan

🇺🇸

Ann Arbor, Michigan, United States

Ascension St. John Hospital

🇺🇸

Grosse Pointe Woods, Michigan, United States

Ascension Providence Hospital Southfield Cancer Center

🇺🇸

Southfield, Michigan, United States

Mayo Clinic

🇺🇸

Rochester, Minnesota, United States

The West Clinic, PLLC dba West Cancer Center,7668 Airways Blvd

🇺🇸

Southaven, Mississippi, United States

The University of Kansas Cancer Center,2750 Clay Edwards Drive

🇺🇸

Kansas City, Missouri, United States

The University of Kansas Cancer Center,8700 North Green Hills Road

🇺🇸

Kansas City, Missouri, United States

The University of Kansas Cancer Center,4881 N.E. Goodview Circle

🇺🇸

Lee's Summit, Missouri, United States

Nebraska Cancer Specialists,2730 W. Faidley Ave

🇺🇸

Grand Island, Nebraska, United States

Nebraska Cancer Specialists,8303 Dodge Street

🇺🇸

Omaha, Nebraska, United States

Nebraska Cancer Specialists

🇺🇸

Omaha, Nebraska, United States

Nebraska Cancer Specialists,611 Fenwick Dr

🇺🇸

Papillion, Nebraska, United States

Comprehensive Cancer Centers of Nevada - Central V,10001 S. Eastern Avenue, Suite 108

🇺🇸

Henderson, Nevada, United States

Comprehensive Cancer Centers of Nevada - Central V,2460 W. Horizon Ridge Parkway

🇺🇸

Henderson, Nevada, United States

Comprehensive Cancer Centers of Nevada - Central V,1501 Wigwam Parkway, Suite 1300

🇺🇸

Henderson, Nevada, United States

Comprehensive Cancer Centers of Nevada - Central V,653 North Town Center Drive, Suite 402

🇺🇸

Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada - Central V,9280 W. Sunset Road Suite 100

🇺🇸

Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada - Central V,7445 Peak Drive

🇺🇸

Las Vegas, Nevada, United States

Comprehensive Cancer Centers of Nevada - Central V

🇺🇸

Las Vegas, Nevada, United States

Summit Medical Group,1 Diamond Hill Road

🇺🇸

Berkeley Heights, New Jersey, United States

Regional Cancer Care Associates - East Brunswick

🇺🇸

East Brunswick, New Jersey, United States

Summit Medical Group

🇺🇸

Florham Park, New Jersey, United States

Rutgers Cancer Institute of New Jersey,150 Bergen St.

🇺🇸

Newark, New Jersey, United States

John Theurer Cancer Center

🇺🇸

Hackensack, New Jersey, United States

Rutgers Cancer Institute of New Jersey,2575 Klockner Road

🇺🇸

Hamilton, New Jersey, United States

Rutgers Cancer Institute of New Jersey,414 Grand Street

🇺🇸

Jersey City, New Jersey, United States

Rutgers Cancer Institute of New Jersey,600 River Avenue

🇺🇸

Lakewood, New Jersey, United States

Rutgers Cancer Institute of New Jersey,94 Old Short Hills Road

🇺🇸

Livingston, New Jersey, United States

Rutgers Cancer Institute of New Jersey,300 Second Ave

🇺🇸

Long Branch, New Jersey, United States

Regional Cancer Care Associates - East Brunswick,9 Centre Drive

🇺🇸

Monroe, New Jersey, United States

Regional Cancer Care Associates - East Brunswick,34-36 Progress Street

🇺🇸

New Brunswick, New Jersey, United States

Rutgers Cancer Institute of New Jersey

🇺🇸

New Brunswick, New Jersey, United States

Rutgers Cancer Institute of New Jersey,201 Lyons Avenue

🇺🇸

Newark, New Jersey, United States

Regional Cancer Care Associates - East Brunswick,75 Veronica Avenue

🇺🇸

Somerset, New Jersey, United States

Rutgers Cancer Institute of New Jersey,110 Rehill Ave

🇺🇸

Somerville, New Jersey, United States

Rutgers Cancer Institute of New Jersey,99 Highway 37 West

🇺🇸

Toms River, New Jersey, United States

Rutgers Cancer Institute of New Jersey,100 State Route 36

🇺🇸

West Long Branch, New Jersey, United States

New York Cancer & Blood Specialists - Port Jeffers,72 East Main St.

🇺🇸

Babylon, New York, United States

New York Cancer & Blood Specialists - Port Jeffers,12 East 86th St, Suite 4

🇺🇸

Bronx, New York, United States

Montefiore Medical Center - Montefiore Medical Park

🇺🇸

Bronx, New York, United States

New York Cancer & Blood Specialists - Port Jeffers,2330 Eastchester Road, Suite 360

🇺🇸

Bronx, New York, United States

Perlmutter Cancer Center - Manhattan - 34th Street,259 First Street

🇺🇸

Mineola, New York, United States

New York Cancer & Blood Specialists - Port Jeffers,1 Delaware Dr.

🇺🇸

New Hyde Park, New York, United States

Perlmutter Cancer Center - Manhattan - 34th Street

🇺🇸

New York, New York, United States

NYP/Columbia Univeresity Medical Center/Herbert Irving Comprehensive Cancer Center

🇺🇸

New York, New York, United States

New York Cancer & Blood Specialists - Port Jeffers,365 East Main St.

🇺🇸

Patchogue, New York, United States

New York Cancer & Blood Specialists - Port Jeffers,1500 Rte, 112, Building 4

🇺🇸

Port Jefferson, New York, United States

The Ohio State University Wexner Medical Center Clinical Laboratories

🇺🇸

Columbus, Ohio, United States

Seoul National University Bundang Hospital

🇰🇷

Seongnam-si, Korea, Republic of

Severance Hospital

🇰🇷

Seoul, Korea, Republic of

Asan Medical Center

🇰🇷

Seoul, Korea, Republic of

Zangmeister Cancer Center

🇺🇸

Columbus, Ohio, United States

Northwest Cancer Specialists, PC,5050 NE Hoyt St.

🇺🇸

Portland, Oregon, United States

Samsung Medical Center

🇰🇷

Seoul, Korea, Republic of

Northwest Cancer Specialists, PC,265 N. Broadway

🇺🇸

Portland, Oregon, United States

Northwest Cancer Specialists, PC

🇺🇸

Tigard, Oregon, United States

Magee-Womens Hospital of UPMC,200 Oxford Drive

🇺🇸

Bethel Park, Pennsylvania, United States

Korea University Anam Hospital

🇰🇷

Seoul, Korea, Republic of

Seoul National University Hospital

🇰🇷

Seoul, Korea, Republic of

The Catholic University of Korea, Seoul St. Mary's Hospital

🇰🇷

Seoul, Korea, Republic of

Hospital Pulau Pinang

🇲🇾

Georgetown, Malaysia

Hospital Sultan Ismail

🇲🇾

Johor Bahru, Malaysia

Hospital Kuala Lumpur

🇲🇾

Kuala Lumpur, Malaysia

Pantai Hospital Kuala Lumpur

🇲🇾

Kuala Lumpur, Malaysia

University Malaya Medical Centre (UMMC)

🇲🇾

Kuala Lumpur, Malaysia

Institut Kanser Negara

🇲🇾

Putrajaya, Malaysia

Hospital Wanita dan Kanak-Kanak Sabah

🇲🇾

Sabah, Malaysia

Sarawak General Hospital

🇲🇾

Sarawak, Malaysia

Icaro Investigaciones en Medicina S.A. de C.V.

🇲🇽

Chihuahua, Mexico

Cryptex Investigación Clínica

🇲🇽

Ciudad de Mexico, Mexico

Centro para el Desarrollo de la Medicina

🇲🇽

Culiacan, Mexico

Panamerican Clinical Research Mexico - Guadalajara

🇲🇽

Guadalajara, Mexico

Medical Care and Research S.A. de C.V

🇲🇽

Merida, Mexico

Avix Investigacion Clinica S.C.

🇲🇽

Monterrey, Mexico

Fucam A.C.

🇲🇽

México, Mexico

Oncológico Potosino

🇲🇽

San Luis Potosi, Mexico

FAICIC Clínical Research

🇲🇽

Veracruz, Mexico

iBiomed - Investigacion Biomedica para el Desarrol

🇲🇽

Zapopan, Mexico

Amphia Ziekenhuis - Breda Langendijk

🇳🇱

Breda, Netherlands

Universitair Medisch Centrum Groningen

🇳🇱

Groningen, Netherlands

Medisch Centrum Leeuwarden

🇳🇱

Leeuwarden, Netherlands

Erasmus Medisch Centrum

🇳🇱

Rotterdam, Netherlands

Uniwersyteckie Centrum Kliniczne, Klinika Onkologii i Radioterapii

🇵🇱

Gdansk, Poland

Narodowy Instytut Onkologii im. Marii Sklodowskiej

🇵🇱

Gliwice, Poland

SP ZOZ Opolskie Centrum Onkologii im. prof. Tadeusza Koszarowskiego

🇵🇱

Opole, Poland

Wielkopolskie Centrum Onkologii im. Marii Sklodowskiej-Curie

🇵🇱

Poznan, Poland

Mazowiecki Szpital Wojewódzki im. w. Jana Pawa II w

🇵🇱

Siedlce, Poland

Wojskowy Instytut Medyczny

🇵🇱

Warsaw, Poland

Narodowy Instytut Onkologii im.Marii Marii Sklodowskiejs

🇵🇱

Warszawa, Poland

Ponce Medical School Foundation Inc.

🇵🇷

Ponce, Puerto Rico

Hopelands Cancer Centre

🇿🇦

Hilton, South Africa

The Medical Oncology Centre of Rosebank

🇿🇦

Johannesburg, South Africa

University of Pretoria

🇿🇦

Pretoria, South Africa

Hospital Teresa Herrera - Materno Infantil

🇪🇸

A Coruña, Spain

Hospital Universitari Dexeus

🇪🇸

Barcelona, Spain

Hospital Clinic Barcelona

🇪🇸

Barcelona, Spain

Hospital Clínic de Barcelona

🇪🇸

Barcelona, Spain

Hospital de la Santa Creu i Sant Pau

🇪🇸

Barcelona, Spain

Hospital Universitari Vall d'Hebrón

🇪🇸

Barcelona, Spain

Hospital Universitario de Basurto

🇪🇸

Bilbo, Spain

Hospital Universitari Arnau de Vilanova

🇪🇸

Lleida, Spain

Hospital General Universitario Gregorio Marañón

🇪🇸

Madrid, Spain

MD Anderson Cancer Centre Madrid

🇪🇸

Madrid, Spain

Hospital Universitario Fundación Jiménez Díaz

🇪🇸

Madrid, Spain

Hospital Universitario Virgen de la Victoria

🇪🇸

Malaga, Spain

Hospital General Universitario Morales Meseguer

🇪🇸

Murcia, Spain

Hospital Unviersitario Virgen del Rocio

🇪🇸

Sevilla, Spain

Hospital Universitario Virgen Macarena

🇪🇸

Sevilla, Spain

Hospital Universitario de Canarias

🇪🇸

Tenerife, Spain

Hospital Clínico Universitario de Valencia

🇪🇸

Valencia, Spain

Kantonsspital Baden

🇨🇭

Baden, Switzerland

Kantonsspital Baselland - Standort Liestal

🇨🇭

Liestal, Switzerland

Kantonsspital Sankt Gallen

🇨🇭

St. Gallen, Switzerland

Kantonsspital Winterthur

🇨🇭

Winterthur, Switzerland

Brust-Zentrum Zurich

🇨🇭

Zürich, Switzerland

Changhua Christian Hospital

🇨🇳

Changhua, Taiwan

Magee-Womens Hospital of UPMC,3 St. Francis Way

🇺🇸

Cranberry Township, Pennsylvania, United States

NHS Lothian

🇬🇧

Edinburgh, United Kingdom

Magee-Womens Hospital of UPMC,2500 West 12th Street

🇺🇸

Erie, Pennsylvania, United States

Magee-Womens Hospital of UPMC,201 State Street, 6 Main

🇺🇸

Erie, Pennsylvania, United States

Magee-Womens Hospital of UPMC,200 Village Drive

🇺🇸

Greensburg, Pennsylvania, United States

Kaohsiung Medical University Chung-Ho Memorial Hospital

🇨🇳

Kaohsiung, Taiwan

Taipei Medical University-Shuang Ho Hospital

🇨🇳

New Taipei City, Taiwan

Chi Mei Hospital, Liouying

🇨🇳

Tainan City, Taiwan

National Cheng Kung University Hospital

🇨🇳

Tainan, Taiwan

Taipei Veterans General Hospital

🇨🇳

Taipei City, Taiwan

National Taiwan University Hospital

🇨🇳

Taipei, Taiwan

Linkou Chang Gung Memorial Hospital

🇨🇳

Taoyuan, Taiwan

Baskent Uni. Dr Turgut Noyan Uyg. ve Aras. Merkezi

🇹🇷

Adana, Turkey

Ankara Il Saglik Mudurlugu SBU Gulhane Egitim Ve A

🇹🇷

Ankara, Turkey

Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital

🇹🇷

Ankara, Turkey

Memorial Ankara Hastanesi

🇹🇷

Ankara, Turkey

Hacettepe Üniversitesi Hastanesi

🇹🇷

Ankara, Turkey

Trakya Universitesi Tip Fakultesi Hastanesi

🇹🇷

Edirne, Turkey

Istanbul Il Saglik Mudurlugu Goztepe Prof. Dr. Sul

🇹🇷

Istanbul, Turkey

Medipol Mega Universite Hastanesi

🇹🇷

Istanbul, Turkey

Ege Universitesi Hastanesi

🇹🇷

Izmir, Turkey

Medicana International Izmir Hastanesi

🇹🇷

İzmir, Turkey

Acibadem Maslak Hastanesi

🇹🇷

Sariyer, Turkey

VKV Amerikan Hastanesi

🇹🇷

Sisli, Turkey

Clinical Trials Unit Lvl 0 Cancer Research UK Beatson Institute

🇬🇧

Glasgow, United Kingdom

Leeds Teaching Hospitals NHS Trust

🇬🇧

Leeds, United Kingdom

: Barts Health NHS Trust, St Hospital

🇬🇧

London, United Kingdom

Royal Free London NHS Foundation Trust

🇬🇧

London, United Kingdom

Guy's and Saint Thomas' NHS Foundation Trust

🇬🇧

London, United Kingdom

University College London Hospitals

🇬🇧

London, United Kingdom

Nottingham University Hospitals NHS Trust

🇬🇧

Nottingham, United Kingdom

Magee-Womens Hospital of UPMC,400 Oxford Drive

🇺🇸

Monroeville, Pennsylvania, United States

University of California Los Angeles - Jonsson Comprehensive Cancer Center,201 S. Buena Vista Street, Suite 200

🇺🇸

Burbank, California, United States

University of California Irvine Health Chao Family,1640 Newport Blvd

🇺🇸

Costa Mesa, California, United States

City of Hope

🇺🇸

Duarte, California, United States

University of California San Diego Moores Cancer

🇺🇸

La Jolla, California, United States

University of California Los Angeles - Jonsson Comprehensive Cancer Center,24302 Paseo de Valencia, Suite 200

🇺🇸

Laguna Hills, California, United States

Cancer and Blood Specialty Clinic

🇺🇸

Los Alamitos, California, United States

City of Hope,1601 Avocado Ave

🇺🇸

Newport, California, United States

University of California Irvine Health Chao Family

🇺🇸

Orange, California, United States

City of Hope,209 Fair Oaks Ave

🇺🇸

Pasadena, California, United States

University of California Los Angeles - Jonsson Comprehensive Cancer Center,892 Aerovista Place, Suite 240

🇺🇸

San Luis Obispo, California, United States

Sansum Clinic

🇺🇸

Santa Barbara, California, United States

University of California Los Angeles - Jonsson Comprehensive Cancer Center,2020 Santa Monica Blvd, Suite 600

🇺🇸

Santa Monica, California, United States

University of California Los Angeles - Jonsson Comprehensive Cancer Center,2336 Santa Monica, Suites 302 and 304

🇺🇸

Santa Monica, California, United States

University of California Los Angeles - Jonsson Comprehensive Cancer Center

🇺🇸

Santa Monica, California, United States

St. Jude Hospital Yorba dba St. Joseph Heritage Healthcare

🇺🇸

Santa Rosa, California, United States

Sansum Clinic,2040 Viborg Road

🇺🇸

Solvang, California, United States

City of Hope,5215 Torrance Blvd

🇺🇸

Torrance, California, United States

Torrance Memorial Physician Network - Cancer Care

🇺🇸

Torrance, California, United States

City of Hope,1100 San Bernardino Rd

🇺🇸

Upland, California, United States

University of California Los Angeles - Jonsson Comprehensive Cancer Center,1250 La Venta Dr, Suite 100

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Westlake Village, California, United States

Rocky Mountain Cancer Centers,1700 South Potomac Street

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Aurora, Colorado, United States

Rocky Mountain Cancer Centers

🇺🇸

Boulder, Colorado, United States

University of Miami - Sylvester Comprehensive Cancer Center,1192 East Newport Center Drive

🇺🇸

Deerfield Beach, Florida, United States

Florida Cancer Specialists

🇺🇸

Fort Myers, Florida, United States

Florida Cancer Specialists,8981 Colonial Center Drive

🇺🇸

Fort Myers, Florida, United States

Florida Cancer Specialists,8260 Gladiolus Dr

🇺🇸

Fort Myers, Florida, United States

SCRI - Florida Cancer Specialists - North Region R,6420 W. Newberry Road

🇺🇸

Gainesville, Florida, United States

University of Miami - Sylvester Comprehensive Cancer Center,3850 Hollywood Blvd

🇺🇸

Hollywood, Florida, United States

SCRI - Florida Cancer Specialists - North Region R,100 Highland Avenue

🇺🇸

Largo, Florida, United States

SCRI - Florida Cancer Specialists - North Region R,521 North Lecanto Highway

🇺🇸

Lecanto, Florida, United States

University of Miami - Sylvester Comprehensive Cancer Center,1400 NW 12th Ave

🇺🇸

Miami, Florida, United States

University of Miami - Sylvester Comprehensive Cancer Center

🇺🇸

Miami, Florida, United States

University of Miami - Sylvester Comprehensive Cancer Center,8932 S.W. 97 Ave

🇺🇸

Miami, Florida, United States

Florida Cancer Specialists,1100 Goodlette Road

🇺🇸

Naples, Florida, United States

SCRI - Florida Cancer Specialists - North Region R,4945 SW 49th Place

🇺🇸

Ocala, Florida, United States

SCRI - Florida Cancer Specialists - North Region R,2824 Enterprise Rd

🇺🇸

Orange City, Florida, United States

Advent Health Medical Group,2501 North Orange Ave

🇺🇸

Orlando, Florida, United States

SCRI - Florida Cancer Specialists - North Region R,70 W. Gore Street

🇺🇸

Orlando, Florida, United States

University of Miami - Sylvester Comprehensive Cancer Center,8100 SW 10 Street

🇺🇸

Plantation, Florida, United States

Florida Cancer Specialists,22395 Edgewater Drive

🇺🇸

Port Charlotte, Florida, United States

SCRI - Florida Cancer Specialists - North Region R,1201 Fifth Avenue North

🇺🇸

Saint Petersburg, Florida, United States

SCRI - Florida Cancer Specialists - North Region R

🇺🇸

Saint Petersburg, Florida, United States

Florida Cancer Specialists,600 North Cattlemen Road

🇺🇸

Sarasota, Florida, United States

Florida Cancer Specialists,1970 Golf Street

🇺🇸

Sarasota, Florida, United States

SCRI - Florida Cancer Specialists - North Region R,7154 Medical Center Drive

🇺🇸

Spring Hill, Florida, United States

SCRI - Florida Cancer Specialists - West Palm Beach,301 SE Ocean Blvd, Suite 102

🇺🇸

Stuart, Florida, United States

Winship Cancer Institute of Emory University

🇺🇸

Atlanta, Georgia, United States

Northside Hospital,5670 Peachtree Dunwoody Rd.

🇺🇸

Atlanta, Georgia, United States

Northside Hospital

🇺🇸

Atlanta, Georgia, United States

Winship Cancer Institute of Emory University,5665 Peachtree Dunwoody Road

🇺🇸

Atlanta, Georgia, United States

Northside Hospital,308 Deep South Farm Rd, Suite 200

🇺🇸

Blairsville, Georgia, United States

Northside Hospital,228 Riverstone Dr.

🇺🇸

Canton, Georgia, United States

Northside Hospital,1505 Northside Blvd, Suite 4600

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Cumming, Georgia, United States

Northside Hospital,3855 Pleasant Hill Rd., Suite 480

🇺🇸

Duluth, Georgia, United States

Northside Hospital,308 Coliseum Dr.

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Macon, Georgia, United States

Piedmont Cancer Institute - Atlanta,775 Poplar Road

🇺🇸

Newnan, Georgia, United States

Piedmont Cancer Institute - Atlanta,1240 Eagles Landing Pkwy

🇺🇸

Stockbridge, Georgia, United States

Robert H. Lurie Comprehensive Cancer Center of Northwestern University

🇺🇸

Chicago, Illinois, United States

University of Illinois Hospital and Health Sciences System (Outpatient Cancer Center)

🇺🇸

Chicago, Illinois, United States

Orchard Healthcare Research Inc,2845 North Sheridan Road, 1st Floor

🇺🇸

Chicago, Illinois, United States

Robert H. Lurie Comprehensive Cancer Center of Northwestern University,1 Kish Hospital Drive

🇺🇸

DeKalb, Illinois, United States

Robert H. Lurie Comprehensive Cancer Center of Northwestern University,10 Health Services Drive

🇺🇸

DeKalb, Illinois, United States

Orchard Healthcare Research Inc,800 Austin Street, Suite 360, East Tower

🇺🇸

Evanston, Illinois, United States

Robert H. Lurie Comprehensive Cancer Center of Northwestern University,300 Randall Road

🇺🇸

Geneva, Illinois, United States

Robert H. Lurie Comprehensive Cancer Center of Northwestern University,304 Randall Road

🇺🇸

Geneva, Illinois, United States

Robert H. Lurie Comprehensive Cancer Center of Northwestern University,1000 N. Westmoreland Road

🇺🇸

Lake Forest, Illinois, United States

Orchard Healthcare Research Inc

🇺🇸

Skokie, Illinois, United States

Robert H. Lurie Comprehensive Cancer Center of Northwestern University,4405 Weaver Parkway

🇺🇸

Warrenville, Illinois, United States

Robert H. Lurie Comprehensive Cancer Center of Northwestern University,4455 Weaver Parkway

🇺🇸

Warrenville, Illinois, United States

Robert H. Lurie Comprehensive Cancer Center of Northwestern University,25 N Winfield Road

🇺🇸

Winfield, Illinois, United States

New York Cancer & Blood Specialists - Port Jeffers,49 Rte. 347, Newconset Hwy

🇺🇸

Port Jefferson Station, New York, United States

New York Cancer & Blood Specialists - Port Jeffers

🇺🇸

Port Jefferson Station, New York, United States

New York Cancer & Blood Specialists - Port Jeffers,750 Old County Rd. Suite 4

🇺🇸

Riverhead, New York, United States

Regulatory Management Only: TRIO-US Central Administration

🇺🇸

Fort Wayne, Indiana, United States

The University of Kansas Cancer Center,2000 Olathe Blvd

🇺🇸

Kansas City, Kansas, United States

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