MedPath

A Comparative Analysis of Portable Bladder Scanner to Determine Age/ Volume Specific Accuracy in 0-6 Years of Children

Completed
Conditions
Detrusor Overactivity
Neurogenic Bladder
Detrusor Underactivity
Interventions
Device: Bladder scan
Registration Number
NCT04543552
Lead Sponsor
Seoul National University Hospital
Brief Summary

As a part of the urodynamic studies, urinary catheterization is inserted to measure residual urine, however, it has shown to be an invasive procedure, cause urinary tract infection, and traumatic experience. Bladder scan has been introduced as an alternative and non-invasive method to measure urine residual in the bladder.

Detailed Description

Functional urinary disorders are common as more than 15% of children are diagnosed. During the normal course of urinary tract development, bladder and urinary sphincter develop by 2 to 4 years old, and by five years old, the tract is completely developed. The underdevelopment of the urinary tract may lead to complications of the bladder and kidneys along with social impairment. Therefore, the diagnosis is critical as an early diagnosis can prevent long term complications. To diagnose, newborns undergo basic urinalysis, urine culture examination, blood creatinine analysis, and kidney and bladder ultrasound. If any abnormalities are present at the under the age of five, it is recommended that they are followed up on a regular basis. Also, urodynamic studies should be performed every year along with others for early identification and intervention. Studies have shown that UDS (urodynamic studies) significantly reduce the deterioration of the bladder and kidney and the need for operation such as bladder dilation.

As a part of the urodynamic studies, urinary catheterization is inserted to measure residual urine, however, it has shown to be an invasive procedure, which can cause urinary tract infection. The bladder scanner is an ultrasonic imaging device that has been developed for non-invasive measurement of residual volume in the bladder. The images and measurements are obtained by applying a probe onto the abdomen. It constructs 12 cross-sectional images at 15 degree interval using the reflection signals from urine in the bladder and extracts the position of the bladder wall.

The objective of the study is to assess the validity of existing pediatric algorithms for diagnosing neurogenic bladder and evaluate the accuracy of measuring the post-void residual volume between the ages of 0 to 6 years old.

It hypothesizes that when the portable bladder scanner (Bladder Scanner, Biocon-900) is used in pediatric population between the ages of 0 to 3 years old will show greater difference in infused and scanned volume than 4 to 6 years old.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
34
Inclusion Criteria
  • Under the age of 6 years old.
  • Urodynamic study is scheduled to due to suspected changes in the bladder function or shape.
  • Those who understand and sign the informed consent form.
Exclusion Criteria
  • Subjects with surgical history of the bladder.
  • Constant leaking of the urine due to bladder neck contracture.
  • Any congenital abnormalities that induce changes in the shape of the bladder.
  • Unsuitable to participate in the study at the discretion of the principal investigator.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Bladder ScanBladder scanSubjects who are scheduled to undergo urodynamic studies.
Primary Outcome Measures
NameTimeMethod
Scanned bladder volumeImmediately after procedure (urodynamics studies)

Measurement of the bladder volume

Drainage volumeImmediately after procedure (urodynamics studies)

Residual urine drained by using a catheter

Estimated Post Void ResidueImmediately after procedure (urodynamics studies)

Estimated PVR

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Seoul National University Hospital

🇰🇷

Seoul, Korea, Republic of

© Copyright 2025. All Rights Reserved by MedPath