EUCTR2006-005951-14-IT进行中（未招募）1 期
A prospective, randomized, open label blinded end point probe trial to evaluate whether, at comparable blood pressure control, combined therapy with the ACE inhibitor Benazepril and the angiotensin II receptor blocker ARB Valsartan reduces progression to ESRD more effectively than Benazepril or Valsartan alone in high risk patients with type 2 diabetes and overt nephropathy VALID Study - VALID Study
IST. DI RICERCHE FARMACOLOG. M. NEGRI0 个研究点目标入组 103 人开始时间: 2007年3月29日最近更新:
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 103
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •-Males and females 40 years old; -High-risk subjects with type 2 diabetes WHO criteria ; -Serum creatinine concentration of 1.8 mg/dl or more but les than 3.5 mg/dl ; -Urinary albumin to creatinine ratio of 2000mg/g or more in spot morning urine ; -Written informed consent.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
排除标准
- •-Specific contraindications or history of hypersensitivity to the study drugs or other; -Serum potassium 8805; 6 mEq/L despite diuretic therapy, and optimized metabolic and acid/base control; -Bilateral renal artery stenosis; -Previous history of allergy or intolerance, or evidence of immunologically-mediated renal disease, systemic diseases, cancer; -Drug or alcohol abuse; -Any chronic clinical conditions that may affect completion of the trial or confound data interpretation; -Pregnancy or lactating; -Women of childbearing potential without following a scientifically accepted form of contraception; -Legal incapacity and/or other circumstances rendering the patient unable to understand the nature, scope and possible consequence of the trial; -Evidence of an uncooperative attitude; -Any evidence that patient will not be able to complete the trial follow-up.
研究者
相似试验
进行中（未招募）
1 期
A prospective, randomized, open label blinded end point probe trial to evaluate whether, at comparable blood pressure control, combined therapy with the ACE inhibitor Benazepril and the angiotensin II receptor blocker ARB Valsartan, reduces the incidence of microalbuminuria more effectively than Benazepril or Valsartan alone in hypertensive patients with type 2 diabetes and high-normal albuminuria VARIETY Study - VARIETY StudyDiabetic nephropathyEUCTR2006-005954-62-ITIST. DI RICERCHE FARMACOLOG. M. NEGRI1,233
进行中（未招募）
1 期
A prospective, randomised, open-label blinded end point (PROBE) trial to evaluate, whether, at comparable blood pressure control, combined therapy with the ACE inhibitor benazepril and the angiotensin II receptor blocker (ARB) valsartan reduces progression to ESRD more effectively than benazepril or valsartan alone in high risk patients with type 2 diabetes and overt nephropathy (VALID study) - VALID studyovert nephropathy in type 2 diabetesEUCTR2006-005951-14-SIItalian Drug Agency103
已完成
3 期
A prospective Randomised, open label, blinded endpoint (PROBE) study to Evaluate DUAL antithrombotic therapy with dabigatran etexilate (110mg and 150mg b.i.d.) plus clopidogrel or ticagrelor vs. triple therapy strategy with warfarin (INR 2.0 - 3.0) plus clopidogrel or ticagrelor and aspirin in patients with non valvular atrial fibrillation (NVAF) that have undergone a percutaneous coronary intervention (PCI) with stentingnon-valvular atrial fibrillation and percutaneous coronary intervention1000752110014523NL-OMON44285Boehringer Ingelheim30
进行中（未招募）
1 期
Evaluation of Dual Therapy with Dabigatran vs. Triple Therapy with Warfarin in Patients with AF that undergo a PCI with StentingPatients with non valvular atrial fibrillation (NVAF) that have undergone a percutaneous coronary intervention (PCI) with stentingMedDRA version: 19.1Level: PTClassification code 10003658Term: Atrial fibrillationSystem Organ Class: 10007541 - Cardiac disordersMedDRA version: 19.1Level: PTClassification code 10065608Term: Percutaneous coronary interventionSystem Organ Class: 10042613 - Surgical and medical proceduresEUCTR2013-003201-26-NLBoehringer Ingelheim bv2,502
进行中（未招募）
1 期
Evaluation of Dual Therapy with Dabigatran vs. Triple Therapy with Warfarin in Patients with AF that undergo a PCI with StentingPatients with non valvular atrial fibrillation (NVAF) that have undergone a percutaneous coronary intervention (PCI) with stentingMedDRA version: 20.0Level: PTClassification code 10003658Term: Atrial fibrillationSystem Organ Class: 10007541 - Cardiac disordersMedDRA version: 20.0Level: PTClassification code 10065608Term: Percutaneous coronary interventionSystem Organ Class: 10042613 - Surgical and medical proceduresEUCTR2013-003201-26-PTnilfarma - União Internacional de Lab. Farmacêuticos, Lda2,502