correlation between the dose of vasopressor and cerebral perfusion in patients of septic shock.
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- We are expecting an inverse correlation between the dose of vasopressor and oxygen saturation of brain.
研究概览
简要总结
This is an open label, non-randomized single group observational single center study.
We are trying to correlate the dose of vasopressor and its effect on oxygen saturation of brain.
There is no intervention required and no financial burden will be put on patient.
There will be total of 60 patients and we are expecting that on increasing dose of vasopressor there will be a decrease in oxygen saturation of brain.
This will help us to find the appropriate dose of vasopressor that does not compromise the oxygen saturation and vital organ perfusion.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)（—）
- 性别
- All
入选标准
- •Patient with sepsis on vasopressor support.
排除标准
- •Refusal to consent.
- •Patient with age less than 18 years.
- •Multi organ dysfunction.
结局指标
主要结局
We are expecting an inverse correlation between the dose of vasopressor and oxygen saturation of brain.
时间窗: Baseline and then 4 hourly.
次要结局
- To find the most effective dose of vasopressor that does not alter the end organ perfusion.(Baseline & after 4 hours)
研究者
Dr Pravin Kumar Das
Dr Ram Manohar Lohia Institute of Medical Sciences