MedPath

Post-marketing Surveillance on the Safety of CabometyxTM in Korean Patients

Completed
Conditions
Hepatocellular Carcinoma
Differentiated Thyroid Carcinoma
Renal Cell Carcinoma
Registration Number
NCT03776123
Lead Sponsor
Ipsen
Brief Summary

The objective of this Post Marketing Surveillance (PMS) is to collect and describe safety and effectiveness profile of Cabometyx™ in real clinical practice setting, according to the approved labelling after the approval of marketing authorization.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
347
Inclusion Criteria
  • Patients who meet 'Indications' of label for Cabometyx™ as monotherapy
  • Patients who are treated with Cabometyx™ for the first time according to label for Cabometyx™ as monotherapy
  • Patients who are aged 18 years or older
  • Patients who are willing to provide written consent after being informed of this surveillance
Exclusion Criteria
  • Patients who are contraindicated for Cabometyx™ based on Cabometyx™ label

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Proportion of patients who had AEs/SAE after Cabometyx™ administrationFrom baseline until 21 days after the last dose of Cabometyx (up to approximately 52 weeks)
Number of patients experiencing Adverse Events (AEs)/ Serious Adverse Events (SAEs) after Cabometyx™ administrationFrom baseline until 21 days after the last dose of Cabometyx (up to approximately 52 weeks)
Number of AEs/SAEs after Cabometyx™ administrationFrom baseline until 21 days after the last dose of Cabometyx (up to approximately 52 weeks)
Secondary Outcome Measures
NameTimeMethod
Progression Free SurvivalFrom baseline until 21 days after the last dose of Cabometyx (up to approximately 52 weeks)
Objective response rateFrom baseline until 21 days after the last dose of Cabometyx (up to approximately 52 weeks)

Trial Locations

Locations (47)

Asan Medical Center (Site B)

🇰🇷

Seoul, Korea, Republic of

Kyungpook National University Chilgok Hospital

🇰🇷

Daegu, Korea, Republic of

Kosin University Gospel Hospital (Site B)

🇰🇷

Pusan, Korea, Republic of

Chungnam National University Hospital

🇰🇷

Daejeon, Korea, Republic of

The Catholic University of Korea, Daejeon ST.Mary's Hospital

🇰🇷

Daejeon, Korea, Republic of

Chonnam National University Hwasun Hospital

🇰🇷

Hwasun, Korea, Republic of

Wonkwang University Hospital

🇰🇷

Iksan, Korea, Republic of

DONG-A University Hospital (Site A)

🇰🇷

Busan, Korea, Republic of

Hallym University Sacred Heart Hospital

🇰🇷

Anyang, Korea, Republic of

The Catholic University of Korea, Uijeongbu ST. Mary's Hospital (site A)

🇰🇷

Gyeonggi-do, Korea, Republic of

Daejeon Eulji Medical center, Eulji University

🇰🇷

Daejeon, Korea, Republic of

Konyang University Hospital

🇰🇷

Daejeon, Korea, Republic of

DONG-A University Hospital (Site B)

🇰🇷

Busan, Korea, Republic of

Daegu Catholic University Medical Center

🇰🇷

Daegu, Korea, Republic of

Hanyang University Seoul Hospital

🇰🇷

Seoul, Korea, Republic of

CHA Bundang Medical Center, CHA University

🇰🇷

Seongnam, Korea, Republic of

Inje University Busan Paik Hospital

🇰🇷

Pusan, Korea, Republic of

Gangdong Kyung Hee University Hospital

🇰🇷

Seoul, Korea, Republic of

Korea University Anam Hospital (Site B)

🇰🇷

Seoul, Korea, Republic of

Severance Hospital, Yonsei University (Site B)

🇰🇷

Seoul, Korea, Republic of

Gangnam Severance Hospital, Yonsei University Health System

🇰🇷

Seoul, Korea, Republic of

The Catholic University of Korea, St. Mary's Hospital

🇰🇷

Incheon, Korea, Republic of

Inje University Haeundae Paik Hospital

🇰🇷

Pusan, Korea, Republic of

Pusan National University Hospital (Site A)

🇰🇷

Pusan, Korea, Republic of

Inje University Sanggye Paik Hospital (Site A)

🇰🇷

Seoul, Korea, Republic of

Asan Medical Center (Site A)

🇰🇷

Seoul, Korea, Republic of

Inje University Sanggye Paik Hospital (Site B)

🇰🇷

Seoul, Korea, Republic of

Severance Hospital, Yonsei University (Site A)

🇰🇷

Seoul, Korea, Republic of

Korea University Ansan Hospital

🇰🇷

Ansan, Korea, Republic of

Chungbuk National University Hospital

🇰🇷

Chungbuk, Korea, Republic of

Keimyung University Dongsan Hospital (Site A)

🇰🇷

Daegu, Korea, Republic of

Keimyung University Dongsan Hospital (Site B)

🇰🇷

Daegu, Korea, Republic of

The Catholic University of Korea, Uijeongbu ST. Mary's Hospital (Site B)

🇰🇷

Gyeonggi-do, Korea, Republic of

Korea University Anam Hospital (Site A)

🇰🇷

Seoul, Korea, Republic of

Gachon University Gil Medical Center

🇰🇷

Incheon, Korea, Republic of

Inha University Hospital

🇰🇷

Incheon, Korea, Republic of

Pusan National University Hospital (Site B)

🇰🇷

Pusan, Korea, Republic of

Kosin University Gospel Hospital (Site A)

🇰🇷

Pusan, Korea, Republic of

Samsung medical center (Site B)

🇰🇷

Seoul, Korea, Republic of

Samsung Medical Center (Site C)

🇰🇷

Seoul, Korea, Republic of

Samsung Medical Centre (Site A)

🇰🇷

Seoul, Korea, Republic of

Samsung Medical Center (Site D)

🇰🇷

Seoul, Korea, Republic of

The Catholic University of Korea, Seoul St. Mary's Hospital

🇰🇷

Seoul, Korea, Republic of

Chung-Ang University Hospital

🇰🇷

Seoul, Korea, Republic of

The Catholic University of Korea, Yeouido St. Mary's Hospital

🇰🇷

Seoul, Korea, Republic of

The Catholic University of Korea, St. Vincent's Hospital

🇰🇷

Suwon, Korea, Republic of

Ulsan University Hospital

🇰🇷

Ulsan, Korea, Republic of

© Copyright 2025. All Rights Reserved by MedPath