Adaptive Family Treatment for Adolescent Anorexia Nervosa
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Anorexia Nervosa
- Sponsor
- Stanford University
- Enrollment
- 90
- Locations
- 2
- Primary Endpoint
- Full remission from AN (%MBW>95)
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
Anorexia Nervosa (AN) has the highest mortality rate compared to any other psychiatric disorder. The most promising treatment for adolescents with AN is family-based treatment (FBT). However, only 50% of patients receiving FBT fully remit at 12-month follow-up. Consequently, providing an alternative therapy early in the treatment course for those not responding to FBT may enhance overall outcome. This study aims to develop a new treatment - Intensive Family-Focused Treatment (IFT) - to improve outcomes in those adolescents, aged 12-18 years, who do not show an early response to FBT.
Investigators
James Dale Lock
Principal Investigator
Stanford University
Eligibility Criteria
Inclusion Criteria
- •Meets DSM-IV criteria for anorexia nervosa
- •Lives with at least one English-speaking parent who is willing to participate
- •Medically Stable
- •Adequate transportation to clinic
- •Proficient at speaking, reading, and writing English
Exclusion Criteria
- •Previous FBT for AN
- •Medical condition that may affect eating or weight
Outcomes
Primary Outcomes
Full remission from AN (%MBW>95)
Time Frame: End of Treatment (6 months)
Weight restoration to at least 95% of Median body weight (calculated by height, weight, gender, and age)
Secondary Outcomes
- Changes in subscale scores of the EDE(End of Treatment (6 months))