Adaptive Family Treatment for Adolescent Anorexia Nervosa
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 90
- 试验地点
- 4
- 主要终点
- Full remission from AN (%MBW>95)
研究概览
简要总结
Anorexia Nervosa (AN) has the highest mortality rate compared to any other psychiatric disorder. The most promising treatment for adolescents with AN is family-based treatment (FBT). However, only 50% of patients receiving FBT fully remit at 12-month follow-up. Consequently, providing an alternative therapy early in the treatment course for those not responding to FBT may enhance overall outcome. This study aims to develop a new treatment - Intensive Family-Focused Treatment (IFT) - to improve outcomes in those adolescents, aged 12-18 years, who do not show an early response to FBT.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 12 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Meets DSM-IV criteria for anorexia nervosa
- •Lives with at least one English-speaking parent who is willing to participate
- •Medically Stable
- •Adequate transportation to clinic
- •Proficient at speaking, reading, and writing English
排除标准
- •Previous FBT for AN
- •Medical condition that may affect eating or weight
结局指标
主要结局
Full remission from AN (%MBW>95)
时间窗: End of Treatment (6 months)
Weight restoration to at least 95% of Median body weight (calculated by height, weight, gender, and age)
次要结局
- Changes in subscale scores of the EDE(End of Treatment (6 months))
研究者
James Dale Lock
Principal Investigator
Stanford University