Adaptive Family Treatment for Adolescent Anorexia Nervosa
- Conditions
- Anorexia Nervosa
- Registration Number
- NCT01579682
- Lead Sponsor
- Stanford University
- Brief Summary
Anorexia Nervosa (AN) has the highest mortality rate compared to any other psychiatric disorder. The most promising treatment for adolescents with AN is family-based treatment (FBT). However, only 50% of patients receiving FBT fully remit at 12-month follow-up. Consequently, providing an alternative therapy early in the treatment course for those not responding to FBT may enhance overall outcome. This study aims to develop a new treatment - Intensive Family-Focused Treatment (IFT) - to improve outcomes in those adolescents, aged 12-18 years, who do not show an early response to FBT.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 90
- Meets DSM-IV criteria for anorexia nervosa
- Lives with at least one English-speaking parent who is willing to participate
- Medically Stable
- Adequate transportation to clinic
- Proficient at speaking, reading, and writing English
- Previous FBT for AN
- Medical condition that may affect eating or weight
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Full remission from AN (%MBW>95) End of Treatment (6 months) Weight restoration to at least 95% of Median body weight (calculated by height, weight, gender, and age)
- Secondary Outcome Measures
Name Time Method Changes in subscale scores of the EDE End of Treatment (6 months) Eating Disorder Examination subscale measures (weight concern, shape concern, dietary restraint) within 1 standard deviation of normative scores.
Trial Locations
- Locations (2)
Stanford University
🇺🇸Stanford, California, United States
University of Chicago
🇺🇸Chicago, Illinois, United States
Stanford University🇺🇸Stanford, California, United States