A Study on the Relationship Between Oxygen Levels in the Blood and Breathing Settings in ICU Patients Using Different Ventilation Methods.

Not yet recruiting

Conditions: Acute respiratory failure,

Registration Number: CTRI/2025/03/083672

Brief Summary: Patient’s with acute respiratory failure admitted to intensive care unit will be enrolled in this prospective observational study. Variables such as, fraction of inspired oxygen (FiO2), partial pressure of arterial oxygen (PaO2), oxygen saturation(SpO2) and perfusion index will be noted from arterial blood gas reports and nurse’s chart respectively. Other vital signs includes SBP, DBP, MAP will also be noted. The calculated SF and PF ratios are recorded, and the correlation between SF and PF is noted in different methods of oxygen administration.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 154

Inclusion Criteria

All adult patients aged 18 to 60 years admitted in ICU with respiratory failure and oxygen supplementation.

Exclusion Criteria

Unreliable pulse oximetry waveform Patients in sever shock with clod clammy peripheries Patient who are at hypothermia Patient with sever congenital heart disease or ejection fraction less than 50 percentage or congestive heart failure.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To determine SpO2/FiO2(SF) ratio and PaO2/FiO2(PF) ratio in different modes of ventilation	Day one after ICU admission

Secondary Outcome Measures

Name	Time	Method
To identify the relationship between SpO2/FiO2(SF) ratio and PaO2/FiO2(PF) ratio	Day one after ICU admission

Trial Locations

Locations (1): SRM Medical College Hospital and Research Centre
🇮🇳
Kancheepuram, TAMIL NADU, India
SRM Medical College Hospital and Research Centre
🇮🇳Kancheepuram, TAMIL NADU, India
Dr C K Swetha ramani
Principal investigator
9884782554
swethark@srmist.edu.in