Differences in ECG- vs. proLonged cardIac MonItor-DeTected Atrial Fibrillation in STROKE Patients
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 366
- 试验地点
- 1
- 主要终点
- Number of Participants with Recurrent Ischemic Stroke at End of available Follow-up Time
研究概览
简要总结
The present study is an investigator-initiated, single-center, retrospective study based on data from the London Ontario Stroke Registry (LOSR), aiming to compare the characteristics and outcomes of ECG-detected and Device-Detected atrial fibrillation in patients with ischemic stroke and transient ischemic attack.
详细描述
Patients with ischemic stroke and transient ischemic attack (TIA) without known atrial fibrillation (AF) are investigated with Prolonged Cardiac Monitoring (PCM) to detect AF. It is unclear if AF detected on 12-lead ECG after stroke occurrence bears the same risk of stroke as Device-detected AF. The investigators hypothesize, that Device-detected AF has a lower risk of ischemic stroke recurrence. The investigators will conduct a retrospective analysis of prospectively collected data from consecutive patients enrolled in the London Ontario Stroke Registry, (Ontario, Canada). The primary outcome will be a recurrent ischemic stroke at the end of the available follow-up window. The investigators will include ischemic stroke and TIA patients with ECG-detected AF and those with Device-detected AF on at least 7 days of Holter monitoring.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age ≥18 years
- •Patient with a diagnosis of ischemic stroke or TIA.
- •ECG-diagnosed AF or PCM-detected AF post ischemic stroke or TIA
排除标准
- •Individuals younger than18 years-old
- •Patients without IS or TIA diagnosis
结局指标
主要结局
Number of Participants with Recurrent Ischemic Stroke at End of available Follow-up Time
时间窗: Duration of follow-up - minimum of 3 months after the first encounter with the stroke team
Documented recurrent ischemic stroke
次要结局
- Prevalence of risk factors, cardiovascular comorbidities, and structural heart disease(Documented at baseline.)
- Death(Duration of follow-up - minimum of 3 months after the first encounter with the stroke team)
- Readmission for decompensated AF or heart failure(Duration of follow-up - minimum of 3 months after the first encounter with the stroke team)