Effect of Intraoperative Muscle Relaxation Depth on Postoperative Sore Throat and Hoarseness After General Anesthesia
试验速览
- 阶段
- 不适用
- 入组人数
- 206
- 试验地点
- 1
- 主要终点
- Overall incidence of postoperative sore throat
研究概览
简要总结
Investigators assess and compare postoperative sore throat and hoarseness in the group maintaining moderate relaxation and deep relaxation during operation.
详细描述
In this sturdy, the deep block is applied when the surgeon requests for deep muscle relaxation to improve surgical field condition in the surgery such as laparotomy known that the deep block is helpful and in the other surgeries, the moderate block is maintained. The investigators assess the postoperative sore throat and hoarseness and compare the effect of muscle relaxation depth in the deep block group and moderate block group in terms of the incidence and severity of postoperative sore throat and hoarseness.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Requirement for mechanical ventilation under general anesthesia
排除标准
- •Hoarseness and sore throat existed before surgery
- •Upper respiratory infection
- •Known or predicted difficult airway
- •Liver, renal disease
- •Requirement of postoperative ventilator care
- •the operation within 2hrs
- •Laparoscopic surgery
- •Other positions except supine during surgery
研究组 & 干预措施
Moderate muscle relaxation
Rocuronium is administered to maintain moderate relaxation during operation. This is conventional muscle relaxation level of this institute.
干预措施: Rocuronium(moderate) (Drug)
Deep muscle relaxation
Rocuronium is administered to maintain deep relaxation during operation.
干预措施: Rocuronium(deep) (Drug)
结局指标
主要结局
Overall incidence of postoperative sore throat
时间窗: Within 24 hrs after operation
The overall cumulative incidence of postoperative sore throat is assessed in the 24-hr evaluation period
次要结局
- The incidence of postoperative sore throat(At 1,6, and 24 hrs after operation)
- The severity of postoperative sore throat(At 1,6, and 24 hrs after operation)
- Incidence and severity of postoperative hoarseness(At 1,6, and 24 hrs after operation)
- Postoperative analgesic consumption(Within 24 hrs after operation)
研究者
Jin-Young Hwang
associate professor
SMG-SNU Boramae Medical Center