HIV Prevention With Adolescents: Neurocognitive Deficits and Treatment Response
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 4
- 主要终点
- Time-Line Follow-Back (TLFB)
研究概览
简要总结
This research is examining how genetic and brain factors play a role in adolescents' health risk behavior as well as studying behaviors that young people engage in that may place them at risk for contracting a sexually transmitted disease like HIV/AIDS, and what kind of educational program works best to reduce these risky behaviors.
详细描述
A baseline assessment is conducted, including a computer questionnaire assessing personality characteristics, attitudes toward and experiences with sex, alcohol, drugs, and cigarettes, among other things. The participant also meets with a therapist to conduct a brief motivational interview at this time. A "Time-Line Follow-Back" is conducted; this notes incidences of sexual intercourse, alcohol use, marijuana use, and cigarette use in a 30-day period. An fMRI is conducted, and a saliva sample is gathered. During the second session of the study, participants are randomly assigned to either a sex and alcohol risk reduction intervention, or a sex risk reduction intervention. After the intervention, participants are contacted at 3 month intervals (3 months later, 6 months later, 9 months later, and 12 months later) to meet. At these "follow-up" meetings, another Time-Line Follow-Back is conducted, along with another computer questionnaire (again assessing attitudes toward and experiences with sex, alcohol, drugs, and cigarettes).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 14 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adolescents age 14-18
- •Involved in Juvenile Justice System OR enrolled in a private school
排除标准
- •Currently taking anti-psychotics
- •Involved in similar intervention-based study (2 similar studies being conducted simultaneously by this lab)
研究组 & 干预措施
SEXUAL PLUS ALCOHOL RISK REDUCTION
Intervention contains information geared toward sexual risk reduction as well as alcohol risk reduction.
干预措施: SEXUAL RISK REDUCTION + ALCOHOL RISK REDUCTION (Behavioral)
INFORMATION-ONLY SEXUAL RISK REDUCTION
Intervention contains information geared toward sexual risk reduction only.
干预措施: INFORMATION-ONLY SEXUAL RISK REDUCTION (Behavioral)
结局指标
主要结局
Time-Line Follow-Back (TLFB)
时间窗: 12-months post-intervention
A Time-Line Follow-Back is a review of a recent 30-day period of the participant's life, wherein they note which days they engaged in any of the following activities: sexual intercourse, alcohol use, marijuana use, cigarette use. Further details are also provided, such as whether a condom was used, how many alcoholic drinks were consumed, etc.
Time-Line Follow-Back (TLFB)
时间窗: 3-months post-intervention
A Time-Line Follow-Back is a review of a recent 30-day period of the participant's life, wherein they note which days they engaged in any of the following activities: sexual intercourse, alcohol use, marijuana use, cigarette use. Further details are also provided, such as whether a condom was used, how many alcoholic drinks were consumed, etc.
Time-Line Follow-Back (TLFB)
时间窗: 6-months post-intervention
A Time-Line Follow-Back is a review of a recent 30-day period of the participant's life, wherein they note which days they engaged in any of the following activities: sexual intercourse, alcohol use, marijuana use, cigarette use. Further details are also provided, such as whether a condom was used, how many alcoholic drinks were consumed, etc.
Time-Line Follow-Back (TLFB)
时间窗: 9-months post-intervention
A Time-Line Follow-Back is a review of a recent 30-day period of the participant's life, wherein they note which days they engaged in any of the following activities: sexual intercourse, alcohol use, marijuana use, cigarette use. Further details are also provided, such as whether a condom was used, how many alcoholic drinks were consumed, etc.
次要结局
- Computer questionnaire(12 months post-intervention)
- Computer questionnaire(3 months post-intervention)
- Computer questionnaire(6 months post-intervention)
- Computer questionnaire(9 months post-intervention)