Efficacy of the Extract of Carica Papaya as an Inhibitor of Streptococcus Mutans in Students of the Faculty of Dentistry in the Year 2018
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Number of Colony Forming units (Stage 2)
研究概览
简要总结
Papaya has effects on oral pathogenic microorganisms, it also has anticoagulant quality, amebicidal action, antimicrobial, bacteriostatic and antifungal activity on different bacteria, especially on Streptococcus mutans, this can be exploited in the dental area. The objective of the study was to determine the efficacy of Carica Papaya peel extract (suckling) as an inhibitor of Streptococcus Mutans in students of the dental faculty of the National University of Caaguazú in 2018.
详细描述
Specific objectives
- To determine the inhibition of the extract of the peel of Carica Papaya (baby) at 3% on Streptococcus Mutans by age and sex grouping.
- To quantify the inhibition of the extract of the peel of Carica Papaya (baby) at 3% on the growth of Streptococcus Mutans before, at 10 minutes and 8 days of use in the experimental group.
- Quantify the inhibition of 0.12% Chlorhexidine Gluconate on the growth of Streptococcus Mutans before, after 10 minutes and 8 days of use in the control group.
- Compare the count of Colony Forming Units (CFU) between both groups.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Participants that signed the informed consent
排除标准
- •allergic to carica papaya
- •ongoing medical or dental treatment that could interfere with the results.
结局指标
主要结局
Number of Colony Forming units (Stage 2)
时间窗: 10 minutes after mouthwash use
After Intervention
Number of Colony Forming units (Stage 3)
时间窗: 8 days after mouthwash use
After Intervention
Number of Colony Forming units (Stage 1)
时间窗: thorough study completion, an average of 24 hours
Before Intervention
次要结局
未报告次要终点
研究者
Julieta María Méndez Romero
Head of Writting and Publication Department, Regional Health Research Institute
Universidad Nacional de Caaguazu