Efficacy of the Extract of Carica Papaya as an Inhibitor of Streptococcus Mutans in Students of the Faculty of Dentistry in the Year 2018
Overview
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Julieta María Méndez Romero
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- Number of Colony Forming units (Stage 2)
Overview
Brief Summary
Papaya has effects on oral pathogenic microorganisms, it also has anticoagulant quality, amebicidal action, antimicrobial, bacteriostatic and antifungal activity on different bacteria, especially on Streptococcus mutans, this can be exploited in the dental area. The objective of the study was to determine the efficacy of Carica Papaya peel extract (suckling) as an inhibitor of Streptococcus Mutans in students of the dental faculty of the National University of Caaguazú in 2018.
Detailed Description
Specific objectives
- To determine the inhibition of the extract of the peel of Carica Papaya (baby) at 3% on Streptococcus Mutans by age and sex grouping.
- To quantify the inhibition of the extract of the peel of Carica Papaya (baby) at 3% on the growth of Streptococcus Mutans before, at 10 minutes and 8 days of use in the experimental group.
- Quantify the inhibition of 0.12% Chlorhexidine Gluconate on the growth of Streptococcus Mutans before, after 10 minutes and 8 days of use in the control group.
- Compare the count of Colony Forming Units (CFU) between both groups.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Prevention
- Masking
- Single (Participant)
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Participants that signed the informed consent
Exclusion Criteria
- •allergic to carica papaya
- •ongoing medical or dental treatment that could interfere with the results.
Outcomes
Primary Outcomes
Number of Colony Forming units (Stage 2)
Time Frame: 10 minutes after mouthwash use
After Intervention
Number of Colony Forming units (Stage 3)
Time Frame: 8 days after mouthwash use
After Intervention
Number of Colony Forming units (Stage 1)
Time Frame: thorough study completion, an average of 24 hours
Before Intervention
Secondary Outcomes
No secondary outcomes reported
Investigators
Julieta María Méndez Romero
Head of Writting and Publication Department, Regional Health Research Institute
Universidad Nacional de Caaguazu