Insulin Dosing in Diabetic Patients With End Stage Renal Disease (ESRD) or Hemodialysis

Completed

• Conditions: Hypoglycemia; Diabetes; Renal Dysfunction; Insulin Dosing

• Registration Number: NCT02083133
• Lead Sponsor: Cook County Health

Brief Summary

The purpose of this study is to assess whether the current recommendation for a 50% dose reduction in insulin for diabetic patients with a creatinine clearance (CrCl) ≤15 mL/min or on hemodialysis results in an increased number of hypoglycemic episodes.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-10-01
• Study First Submitted: 2014-03-07
• Study First Submitted QC: 2014-03-07
• Study First Posted: 2014-03-11
• Primary Completion: 2017-01-15
• Study Completion: 2017-05-17
• Status Verified: 2023-06
• Last Update Submitted: 2023-06-16
• Last Update Posted: 2023-06-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 496

Inclusion Criteria

• Inpatient men and women 18 years of age and older with a diagnosis of type 2 diabetes mellitus (T2DM) with CrCl ≥60, 16-59 or ≤15 milliliters/minute.

Exclusion Criteria

• Patients less than 18 years of age, pregnant patients

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Hypoglycemia	Last 5 years

Trial Locations

Locations (1)

John H Stroger Hospital of Cook County; 🇺🇸 Chicago, Illinois, United States