A Clinical trail to evaluate the effect of Ayurvedic medicines (Mahamanjishthadi kwath, Kaishora guggulu, Panchatikta ghrita, Eranda taila) in the management of ekakushtha W.S.R. to psoriasis.
- Conditions
- Other disorders of skin and subcutaneous tissue in diseases classified elsewhere. Ayurveda Condition: EKAKUSHTHAH,
- Registration Number
- CTRI/2023/06/053671
- Lead Sponsor
- Government Akhandanand Ayurveda College
- Brief Summary
CLINICAL EVALUTION OF AYURVEDIC INTERVENTION (MAHAMANJISHTHADI KWATHA, KAISHORA GUGGULU, PANCHATIKTA GHRITA, ERANDA TAILA) IN THE MANAGEMENT OF EKAKUSHTHA W.S.R. TO PSORIASIS.
Patients will be diagnosed on the basis of classical signs and symptoms of Ekakushtha described in Ayurvedic classics and clinical tests like - PASI score, Auspitz sign, Kobner’s phenomena, Candle grease sign. Total 30 patients will be included in trail based on inclusion, exclusion criteria. Initially Koshtha suddhi will be done by erandataila for 3days then trail drugs - Mahamanjishthadi kwath, Kaishora guggulu, Panchatikta ghrita will be given for 6 weeks and weekly koshtha suddhi will be done by eranda taila. Patient assessement will be done based on subjective and objective criteria.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 30
- Patients having clinical signs & symptoms of Ekakushtha.
- Patients having chronicity less than ten years duration.
- Chronicity more than ten years.
- Pregnant and Lactating women.
- Patients with psoriatic arthropathy.
- Patients with uncontrolled DM and HTN.
- K/C/O severe heart diseases, kidney diseases, stroke, liver diseases K/C/O severe systemic illness like R.A., Gout, S.L.E. etc.
- K/C/O pulmonary dysfunction or COPD Patients with history of any acute or chronic infectious diseases like TB, AIDS, Other STDs. Patients taking medications like corticosteroids, hormonal therapy, anti-depressants or any other drugs which may affect outcome of the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Aswedanam (Anhydrosis) Weekly assessment will be done for 6 weeks during trail & for 2 weeks after drug trail. Results will be assessed on the basis of sign & symptoms of Ekakushtha. Weekly assessment will be done for 6 weeks during trail & for 2 weeks after drug trail. Mahavastu (Extensive lesion) Weekly assessment will be done for 6 weeks during trail & for 2 weeks after drug trail. Matsyashakalopamam (Scalig) Weekly assessment will be done for 6 weeks during trail & for 2 weeks after drug trail. Kandu (Itching) Weekly assessment will be done for 6 weeks during trail & for 2 weeks after drug trail. Rukshata (Dryness) Weekly assessment will be done for 6 weeks during trail & for 2 weeks after drug trail.
- Secondary Outcome Measures
Name Time Method Results will be assessed on the basis of PASI score, DLQI, Candle grease sign, Auspitz sign, Kobners phenomena Weekly assessment will be done for 6 weeks during trail & for 2 weeks after drug trail
Trial Locations
- Locations (1)
Government Akhandanand Ayurveda College
🇮🇳Ahmadabad, GUJARAT, India
Government Akhandanand Ayurveda College🇮🇳Ahmadabad, GUJARAT, IndiaAlpesh MunjaniPrincipal investigator8238223403alpeshmunjani2012@gmail.com