Accuracy of Automatic Contusion Volume Scanning for Predicting the Incidence of Pneumonia in Patients With Thoracic Trauma
- Conditions
- PneumoniaThoracic Trauma
- Registration Number
- NCT06750822
- Lead Sponsor
- Azienda Usl di Bologna
- Brief Summary
The goal of this retrospective observational study is to evaluate the diagnostic accuracy of pulmonary contusion volume in predicting early pneumonia in patients with thoracic trauma.
The primary question we aim to answer is: What is the diagnostic accuracy of pulmonary contusion volume in predicting pneumonia within 7 days post-trauma?
Moreover, we aim to explore which is the overlap between the contused segments and those developing pneumonia.
Finally, we aim to explore relevant differences in radiomic features between contused segments that developed pneumonia.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 486
- Admission to the ED for trauma as primary diagnosis
- Whole-body contrast CT scan performed within 6 hours from admission
- Age <18 years
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 7d-pneumonia 7 days Pneumonia appearing within 7 days from trauma, defined as:
• New or worsening pulmonary infiltrates plus ≥ 2 of the following:
* Body temperature ≥ 38°C or ≤ 35°C
* White Blood Cell (WBC) count \> 12,000 or \< 4,000 cells/mL or presence of immature granulocytes in the blood sample
* Purulent sputum
* Worsening pulmonary oxygenation, defined as a decline in the PaO2/FiO2 ratio
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Maggiore Hospital Carlo Alberto Pizzardi
🇮🇹Bologna, BO, Italy