Comparison of analgesic effectiveness of Dexmedetomidine versus Clonidine as an adjuvant to bupivacaine in epidural anaesthesia in patients undergoing vaginal hysterectomy
Phase 1
- Conditions
- Health Condition 1: - Health Condition 2: N813- Complete uterovaginal prolapse
- Registration Number
- CTRI/2020/07/026769
- Lead Sponsor
- Department of anaeshesiology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
ASA grade 1 and 2
Patients body weight 40-70 kg
Patient height >140 cm
undergoing vaginal hysterectomy
Exclusion Criteria
Patient not willing to give consent
Chronic history of headache backache and raised ICP. Heart block, significant bradyarrhythmias, LVF, hematological disease, deranged bleeding or coagulation profile, compromised renal, cardiac or respiratory status.
H/o spinal surgery, spinal deformity or infection at local site.
Diabetes, psychiatric illness, H/o drug abuse
Allergic to any of concerned drugs
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method to evaluate difference in time duration of requirement of first rescue analgesia and total number of rescue analgesias postoperatively in both the groupsTimepoint: 240 min
- Secondary Outcome Measures
Name Time Method to assess and compare mean duration of motor block in both groupsTimepoint: 30 min;to assess and compare mean duration of sensory block in both the groupsTimepoint: 20 min;to assess and compare number of % of cases who experience side effectsTimepoint: 2 hrs;to assess and compare the hemodynamic response intraoperativelyTimepoint: 2 hrs