arrow band imaging versus white light enteroscopy for detection of inflammation in small bowel in patients with Crohn*s disease

• Conditions: Crohn's disease localisation in small bowel; gastrointestinal bleeding; 10017969

• Registration Number: NL-OMON32943
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

Individuals eligible for inclusion are patients with age 18 years or older, with known Crohn's disease or iron deficiency anemia.

Exclusion Criteria

Age under 18 years of age.
Medical and psychological contraindications for enteroscopy.
Patients unable or not willing to give informed consent.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Comparison of NBI enteroscopy with WLE in detection and grading of CD<br /><br>inflammation in small bowel, using findings on histopathology as the<br /><br>gold-standard for mucosal inflammation.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Correlation of endoscopic findings with clinical findings.<br /><br>Correlation of endoscopic findings with immunohistochemical analysis of<br /><br>immunocompetent cells and mRNA levels of proinflammatory cytokines.</p><br>