Comparison of Procedural Sequences in Same-day Painless Bidirectional Endoscopy With Colonoscopic Water Exchange Method

Not Applicable

Completed

• Conditions: Colon Disease; Bidirectional Endoscopy
• Interventions: Behavioral: colonoscopy first; Behavioral: EGD first

• Registration Number: NCT03638713
• Lead Sponsor: Dalin Tzu Chi General Hospital

Brief Summary

This prospective randomized controlled trial is to compare evaluate the optimal procedure sequence among patients undergoing water exchange colonoscopy.

Detailed Description

Same-day esophagogastroduodenoscopy (EGD) and colonoscopy (bidirectional endoscopy; BDE) are commonly performed to evaluate for gastrointestinal conditions, such as active gastrointestinal bleeding, iron deficiency anemia, positive fecal occult blood tests and abdominal pain. EGD-colonoscopy sequence seems to be the reasonable choice for BDE using air or CO2. With the use of water exchange method, endoscopists have to remove the dirty fecal material and air bubble during insertion. Gas insufflated during EGD may get into the colon and make subsequent water exchange colonoscopy more difficult. The aim of this prospective randomized controlled trial is to compare evaluate the optimal procedure sequence among patients undergoing water exchange colonoscopy.

Study Timeline

• Study Start: 2018-05-01
• Study First Submitted: 2018-07-02
• Study First Submitted QC: 2018-08-16
• Study First Posted: 2018-08-20
• Primary Completion: 2021-01-01
• Study Completion: 2021-02-28
• Status Verified: 2022-03
• Last Update Submitted: 2022-03-24
• Last Update Posted: 2022-03-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

• Patients underwent fully sedated bidirectional endoscopy in the physical check-up department

Exclusion Criteria

• Patients who < 18 years old, > 80 years old
• Without standard colon preparation
• Allergy to meperidine or propofol
• With a history of partial colectomy
• Refusal to provide written informed consent
• American Society of Anesthesiology (ASA) risk Class 3 or higher

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
colonoscopy first group	colonoscopy first	Patients received water-exchange colonoscopy first and followed by esophagogastroduodenoscopy
EGD first group	EGD first	Patients received esophagogastroduodenoscopy first and followed by water-exchange colonoscopy

Primary Outcome Measures

Name	Time	Method
cecal insertion time	30 minutes	Cecal insertion time was defined as the time from insertion into the rectum to the time when the colonoscope tip passed to a point proximal to the ileocecal valve so that the base of cecum was visible.

Trial Locations

Locations (1)

Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation; 🇨🇳 Taipei, Taiwan