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Handgrip Exercise for Arteriovenous Fistula Maturation

Not Applicable
Completed
Conditions
Chronic Kidney Disease
Interventions
Other: Post operative progressive handgrip exercise
Other: Treatment as usual
Registration Number
NCT01061008
Lead Sponsor
Bangor University
Brief Summary

The purpose of this study is to investigate whether post operative progressive forearm exercise is effective in improving arteriovenous fistula maturation in chronic kidney disease patients.

Detailed Description

The arteriovenous fistula is considered to be the gold standard form of access for haemodialysis patients, however only 37% of haemodialysis patients have this form of access. A possible explanation for this could be the high fistula failure rate due to the lack of maturation. Therefore interventions aimed at enhancing fistula maturation are warranted. One such intervention could be forearm exercise, however this recommendation is not evidence based. Therefore, the purpose of this study is to investigate whether a program of post operative progressive hand grip exercise can improve fistula maturation.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
31
Inclusion Criteria
  • Stage 4-5 chronic kidney disease, attending for arteriovenous fistula creation in forearm
Exclusion Criteria
  • Are under the age of 18years;
  • Not able to exercise forearm safely (as decided by the patients consultant)
  • Have any other uncontrolled medical condition
  • Unable to withstand transiently raised systolic blood pressure by 35 mmHg and diastolic by 25 mmHg
  • Or are unable to give consent

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Handgrip exercisePost operative progressive handgrip exerciseHandgrip exercise - patients allocated to this intervention will carry out an eight week post operative progressive handgrip exercise training program
Treatment as usualTreatment as usual-
Primary Outcome Measures
NameTimeMethod
Venous Diameter.3 months

Measurements were made using duplex ultrasonagraphy. Measurements were made at predetermined distances 5 to 10 cm proximal to the anastomosis (dependent on wound dressings and turbulent flow around the anastomosis). The scanning position for each patient was traced using transparent sheets which allowed analogous measurement positions for all scans. Cross sectional vascular diameter measurements were made using conventional grey scale B Mode imaging. Diameters were measured from the inner edges of the vascular wall (Wiese \& Nonnast-Daniel, 2004).

Secondary Outcome Measures
NameTimeMethod
Handgrip Endurance3 months
Maximum Handgrip Strength3 months
Forearm Muscle Cross Sectional Area3 months

Trial Locations

Locations (1)

Renal unit, Ysbyty Gwynedd, North West Wales NHS Trust

🇬🇧

Bangor, Gwynedd, United Kingdom

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