TCTR20240520004尚未招募3 期
Efficacy of intratympanic sodium thiosulfate gel injection to preventisplatin-induced ototoxicity: a randomized controlled trial
Faculty of Medicine, Prince of Songkla University0 个研究点目标入组 43 人开始时间: 2024年5月20日最近更新:
适应症
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 43
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20 Years 至 N/A (No limit)（—）
- 性别
- All
入选标准
- •1. Age 20 years and above
- •2. Head and neck cancer patients with confirmed histology
- •3. Plan to receive high dose cisplatin (> 100 mg mg/m2/cycle) treatment as adjuvant, neoadjuvant or palliative chemotherapy
排除标准
- •1. Nasopharyngeal cancer and others cancer which mass obstructing eustachian tube
- •2. History of ear disease, head trauma or prior ear surgery
- •3. Abnormal tympanic membrane or narrow ear canal of any ear
- •4. Asymmetrical hearing at baseline (definition is the asymmetry between two ears of more than 10 dB at any frequency)
- •5. Hearing loss at baseline PTA > 55 dB (Moderately severe sensorineural hearing loss)
- •6. History of any significant drug allergy (such as anaphylaxis or hepatotoxicity) to the excipients of the study medications (STS, hyaluronic acid)
研究者
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