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临床试验/NCT05903547
NCT05903547
已完成
不适用

Glue Versus Subcuticular Suture for Cesarean Closure: a Randomized Control Trial

Columbia University1 个研究点 分布在 1 个国家目标入组 151 人2023年8月23日

概览

阶段
不适用
干预措施
Dermabond Prineo
疾病 / 适应症
Cesarean Section
发起方
Columbia University
入组人数
151
试验地点
1
主要终点
Patient Scar Satisfaction Scale Score
状态
已完成
最后更新
2个月前

概览

简要总结

The aim of this study is to compare cesarean incision outcomes between patients with incision closed with the Dermabond Prineo system compared to standard subcuticular suture.

详细描述

The purpose of this study is to assess patient satisfaction with their incision after undergoing cesarean delivery. Patient satisfaction with their cesarean scar at 4-6 weeks after their surgery will be compared amongst women receiving skin closure with the Dermabond Prineo skin adhesive system versus standard subcuticular suture. Dermabond Prineo has been shown to have improved cosmesis outcomes in non-obstetric populations but has not yet been studied for women receiving cesarean section. In addition to scar appearance, outcomes such as wound infection, postoperative pain, and operative time will be assessed.

注册库
clinicaltrials.gov
开始日期
2023年8月23日
结束日期
2025年2月5日
最后更新
2个月前
研究类型
Interventional
研究设计
Parallel
性别
Female

研究者

责任方
Sponsor
主要研究者

Russell Miller

Sloane Hospital for Women Associate Professor of Prenatal Pediatrics

Columbia University

入排标准

入选标准

  • Women age 18 years or older
  • All women scheduled for primary or repeat cesarean deliveries
  • All women undergoing intrapartum or antepartum cesarean delivery
  • Pfannenstiel skin incision
  • Birth of a live infant at time of cesarean delivery

排除标准

  • Vertical skin incision
  • Cesarean hysterectomy
  • Emergency or stat cesarean delivery excluding standard preoperative preparation measures (i.e., use of Chlorhexidine skin prep, vaginal prep, etc)
  • Intrapartum stillbirth
  • Planned postpartum follow up at another facility
  • Contraindications to routine postpartum pain medications
  • Adhesive or tape allergy

研究组 & 干预措施

Dermabond Prineo Group

At time of cesarean delivery, patients in the Dermabond Prineo group will undergo skin closure with the Dermabond Prineo skin adhesive system.

干预措施: Dermabond Prineo

Suture Group

At time of cesarean delivery, patients in the Suture group will undergo skin closure with standard subcuticular suture.

干预措施: Suture

结局指标

主要结局

Patient Scar Satisfaction Scale Score

时间窗: Assessed at 6-weeks postpartum

The patient's satisfaction with their cesarean incision will be assessed using the validated Patient Scar Assessment Scale (PSAS) questionnaire. The PSAS is a 6-item questionnaire that is scored on a 1 (no complaints/as normal skin) to 10 (worst imaginable/very different from normal skin) scale. Total scores range from 6-60, with a lower score indicating a greater level of patient satisfaction.

次要结局

  • Incidence of Surgical Site Infection (SSI)(Assessed during delivery hospitalization and at 6-week follow-up)
  • Skin Closure Time(Intraoperative)
  • Operative Time(Intraoperative)

研究点 (1)

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