NCT02839278CompletedNot Applicable
Biological Evaluation of a Novel Anti-inflammatory Treatment in Immune-mediated Inflammatory Diseases
Centre Hospitalier Universitaire de Besancon1 site in 1 country150 target enrollmentStarted: April 2015Last updated:
Conditions
Interventions
Drugs
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 150
- Locations
- 1
- Primary Endpoint
- Expression of costimulatory molecules CD86, CD80, CD40 and class II (HLA-DR) on monocytes
Study Overview
Brief Summary
The aim of the study is to investigate in vitro the impact of a novel anti-inflammatory treatment on costimulatory molecules expressed on monocytes.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Basic Science
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 85 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Immune-mediated inflammatory disease (non-ST segment elevation myocardial infarction, Rheumatoid arthritis, Chronic obstructive pulmonary disease, Idiopathic pulmonary fibrosis, Crohn's disease, Ulcerative colitis, Cystic fibrosis, Psoriasis, Multiple sclerosis or major depressive episode)
- •Patient able to understand the reason of the study
- •Patient not opposed to the conservation of biological samples for scientific research
Exclusion Criteria
- •Pregnant woman
- •Subject without health insurance
Arms & Interventions
Immune-mediated inflammatory disease
Experimental
Patients with an immune-mediated inflammatory disease. A blood sample is achieved at T0 (no follow-up).
Intervention: Blood sample (Biological)
Outcomes
Primary Outcomes
Expression of costimulatory molecules CD86, CD80, CD40 and class II (HLA-DR) on monocytes
Time Frame: 24 months
Secondary Outcomes
No secondary outcomes reported
Investigators
Study Sites (1)
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