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SpineJack System Postmarket Registry

Completed
Conditions
Osteoporotic Vertebral Compression Fractures
Interventions
Procedure: SpineJack system
Procedure: Balloon kyphoplasty
Procedure: Vertebroplasty
Registration Number
NCT04795765
Lead Sponsor
Stryker Instruments
Brief Summary

This postmarket registry is intended to prospectively collect real world data to support ongoing safety and performance of the SpineJack system.

Detailed Description

The SpineJack System Registry will employ a prospective, multicenter, observational, consecutive enrollment design. The sample size for this Registry will include at least 400 patients treated for VCFs across approximately 10 sites. A total of 240 patients will be treated with the SpineJack system and 160 patients will be treated with other vertebral augmentation (VA) procedures, such as BKP or VP. Sites within the U.S. may include healthcare professionals (HCPs) that are surgeons, pain physicians and/or interventional radiologists.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
261
Inclusion Criteria
  1. 18 years of age or older
  2. Understand and sign the informed consent form (as applicable)
  3. Exhibit no altered mental status or language barrier that may prevent completion of the patient reported outcome (PRO) surveys following the procedure.
  4. VCF diagnosis made and/or confirmed at participating site.
Exclusion Criteria

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Patients treated with SpineJack systemSpineJack systemSpineJack system procedure
Patients treated with vertebral augmentationVertebroplastyVertebral augmentation procedures may include either balloon kyphoplasty (BKP) or vertebroplasty (VP).
Patients treated with vertebral augmentationBalloon kyphoplastyVertebral augmentation procedures may include either balloon kyphoplasty (BKP) or vertebroplasty (VP).
Primary Outcome Measures
NameTimeMethod
Back pain12 months post-procedure

The numeric rating scale consists of an eleven-point scale used for patient self-reporting of back pain, which ranges from 0 (no pain) to 10 (the worst pain imaginable).

Radiological outcomesImmediately post-procedure

Adjacent level fractures

Adverse events12 months post-procedure

1. Incidence of adverse device effects (ADEs) and serious adverse device effects (SADEs) requiring surgical re-intervention or re-treatment at the treated level

2. Incidence of unanticipated ADEs

3. Incidence of procedure-related AEs

Quality of life indices - Roland Morris Disability Questionnaire (RMDQ)12 months post-procedure

24-item self-report questionnaire used in patients with mild to moderate disability due to acute, sub-acute or chronic low back pain

Patient-Reported Outcomes Measurement Information System (PROMIS Global-10)12 months post-procedure

10-item questionnaire that is used to assess general domains of health and functioning, including overall physical health, mental health, social health, pain, fatigue and overall perceived quality of life

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (12)

San Diego Neurosurgery

🇺🇸

Encinitas, California, United States

California Orthopedics and Spine

🇺🇸

Larkspur, California, United States

Icahn School of Medicine at Mount Sinai

🇺🇸

New York, New York, United States

Dartmouth Hitchcock

🇺🇸

Lebanon, New Hampshire, United States

Cleveland Clinic

🇺🇸

Stuart, Florida, United States

Clinical Investigations

🇺🇸

Edmond, Oklahoma, United States

Center for Diagnostic Imaging (CDI)

🇺🇸

Puyallup, Washington, United States

Rainier Orthopedic Institute

🇺🇸

Puyallup, Washington, United States

Medical College of Wisconsin

🇺🇸

Milwaukee, Wisconsin, United States

St. Luke's IntermountainResearch Center

🇺🇸

Boise, Idaho, United States

Wake Forest Baptist Health

🇺🇸

Winston-Salem, North Carolina, United States

Montefiore Medical Center

🇺🇸

Bronx, New York, United States

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