nveiling the Human Virome post Kidney Transplantation – Insights into Shifting Viral Landscapes and Potential Health Consequences
Recruiting
- Conditions
- Z94.0Kidney transplant status
- Registration Number
- DRKS00033759
- Lead Sponsor
- ierenzentrum Heidelberg
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 300
Inclusion Criteria
de-novo/re-transplanted
-present consent
Exclusion Criteria
-no biomaterial available
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Investigate changes in the human virome in sequencing data of biomaterial from kidney transplant patients in longitudinal section and compare the viral composition before transplantation with 3/6/12/36 months after transplantation
- Secondary Outcome Measures
Name Time Method -Differences between polyomavirus genotypes in relation to the development of BK nephropathy<br>-Association of certain viral genotypes with certain types of cancer at the time of initial diagnosis Malignancy
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms drive viral landscape shifts in post-kidney transplant patients?
How do virome changes correlate with immune suppression levels in DRKS00033759 participants?
Are specific viral biomarkers predictive of graft dysfunction or rejection in kidney transplant recipients?
What adverse events are associated with virome alterations following kidney transplantation?
How does the human virome interact with immunosuppressive drug classes like calcineurin inhibitors post-transplant?