Evaluation of the effect of melatonin(sleep-wake regulating hormone) premedication on preoperative anxiety, propofol(general anaesthetic) induction dosage, perioperative haemodynamics(blood pressure,heart rate) and quality of recovery : An exploratory study
Phase 3
- Registration Number
- CTRI/2021/09/036209
- Lead Sponsor
- Manasmita Dalai
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. ASA-I, I
2. Female Patient
3. 18 to 65 years of age undergoing elective laparoscopic gynaecological surgery
Exclusion Criteria
1. patient not willing to participate
2. significant cardiac, hepatic renal dysfunction
3. allergy to study drugs
4. Patient with a history of chronic use of sedatives or analgesics especially
opioids and gabapentinoids
5. patients requiring post operative ventilatory support
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Preoperative anxiety and sedation <br/ ><br>2.Quality of recovery (QoR 15 score) <br/ ><br> <br/ ><br>Timepoint: From time in preoperative room till 24hour of surgery <br/ ><br>
- Secondary Outcome Measures
Name Time Method 1. Induction dosage of propofol <br/ ><br> <br/ ><br>2.Perioperative haemodynamic effectsTimepoint: From start of induction till 24 hour after surgery