The Impact of Preoperative Anemia on Postoperative Anemia and Related Nutrient Abnormalities After Bariatric Surgery
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Anemia
- Sponsor
- China-Japan Friendship Hospital
- Enrollment
- 400
- Locations
- 1
- Primary Endpoint
- Odds ratio (OR) for anemia by preoperative anemia status
- Status
- Completed
- Last Updated
- 9 months ago
Overview
Brief Summary
This study aims to assess the impact of preoperative anemia status on anemia and related nutrient abnormalities 1 year after bariatric surgery.
Detailed Description
This study aims to assess the impact of preoperative anemia status on anemia and related nutrient abnormalities (ferritin deficiency, vitamin B12 deficiency, folate deficiency, and low transferrin saturation level) at 1 year after bariatric surgery.
Investigators
Yuntao Nie
Principal Investigator
China-Japan Friendship Hospital
Eligibility Criteria
Inclusion Criteria
- •Patients who underwent bariatric surgery (sleeve gastrectomy and Roux-en-Y gastric bypass)
- •Age between 16 and 70 years
- •Patients who have complete 1-year follow-up data
Exclusion Criteria
- •Baseline renal failure
- •Vegetarian
- •Postoperative bleeding (it was defined as a drop in hemoglobin levels \> 3 g/dL or a confirmed blood loss requiring treatment after surgery)
Outcomes
Primary Outcomes
Odds ratio (OR) for anemia by preoperative anemia status
Time Frame: 1 year
Multivariable logistic regression will be performed to assess the association between preoperative anemia and postoperative anemia. Several factors will be adjusted: sex, age, BMI, waist circumference, hip circumference, surgery, smoking, alcohol, hypertension, diabetes, hyperuricemia, hypercholesterolemia, and hypertriglyceridemia.
Secondary Outcomes
- Percentage of ferritin deficiency(1 year)
- Percentage of anemia severity(1 year)
- Percentage of postoperative anemia(1 year)
- Percentage of folate deficiency(1 year)
- Percentage of vitamin B12 deficiency(1 year)
- Percentage of low transferrin saturation level(1 year)