A Comparison of Volatile Anesthesia and Total Intravenous Anesthesia (TIVA)

Completed

• Conditions: Ecchymosis; Edema; Hemorrhage; Rhinoplasty
• Interventions: Other: Different anesthesia methods

• Registration Number: NCT04773002
• Lead Sponsor: Tokat Gaziosmanpasa University

Brief Summary

In this study, investigators wanted to investigate the effect of volatile anesthesia and total intravenous anesthesia (TIVA) on ecchymosis, edema, and intraoperative bleeding in rhinoplasty.

Detailed Description

Routine monitorization (blood pressure, pulse, oxygen saturation with pulse oximetry and electrocardiogram) will be applied to all patients taken into the operation room.

In Group P (TIVA), induction of anesthesia will be achieved with 2 mg/kg propofol, 0.6 mg/kg rocuronium, and 1 μ / kg fentanyl. Propofol and remifentanil will be used in the continuation of anesthesia.

In Group S (Volatile), anesthesia will be induced with 2 mg / kg propofol, 0.6 mg / kg rocuronium and 1 μ / kg fentanyl. 50% nitrous oxide + 50% oxygen and 2% sevoflurane will be used in the continuation of anesthesia.

All patients will receive 2 ml/kg/hour Ringer's lactate solution during the operation.

Study Timeline

• Study First Submitted: 2021-02-23
• Study First Submitted QC: 2021-02-23
• Study First Posted: 2021-02-26
• Study Start: 2021-03-18
• Primary Completion: 2021-08-21
• Study Completion: 2021-08-21
• Status Verified: 2022-03
• Last Update Submitted: 2022-03-15
• Last Update Posted: 2022-03-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

• Between 18 and 65 years
• Planned to rhinoplasty
• An American Society of Anesthesiologists score of 1 or 2

Exclusion Criteria

• Steroid use
• Patients with coagulation disorders, •Rejected to participation

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Group P	Different anesthesia methods	Total intravenous anesthesia (TIVA)
Group S	Different anesthesia methods	Volatile anestesia

Primary Outcome Measures

Name	Time	Method
Edema and ecchymosis in rhinoplasty according to the type of anesthesia.	one time in six months	It is evaluation developing edema and ecchymosis according to total intravenous anesthesia and volatile anesthesia in rhinoplasty.

Trial Locations

Locations (1)

Gaziosmanpasa University; 🇹🇷 Tokat, Turkey