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To check efficacy of ripasudil in management of primary open angle glaucoma

Not Applicable
Conditions
Health Condition 1: 4- Measurement and MonitoringHealth Condition 2: H401- Open-angle glaucoma
Registration Number
CTRI/2021/05/033754
Lead Sponsor
Dr Sowparnika A B
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1. Newly detected POAG / OHT.

2. POAG will be defined as:

a. IOP > 21 mmHg on atleast 2 occasions, atleast 24 has apart.

b. Optic nerve head showing CDR > 0.61 with significant thinning of the neuroretinal rim: or a CDR asymmetry of 0.2 > between 2 eyes.

c. Open angles on gonioscopy.

d. Automated visual field testing showing changes corresponding with the optic disc changes.

3. OHT will be defined as:

• IOP > 21 mmHg on atleast 2 occasions, 24 hrs apart.

• Open angles on gonioscopy

• Normal optic disc and visual field tests

4. Patients willing to participate in the study given a written informed consent and comply with the followup schedule.

Exclusion Criteria

1. Patients with POAG / OHT having IOP > 30 mmHg.

2. Patient with PACG and others secondary glaucoma.

3. Patient underwent surgery on the inner eye

4. Patient who changed glaucoma treatment after ripasudil administration

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
measurement of IOPTimepoint: day 14, 1 month, 2months and 3 months
Secondary Outcome Measures
NameTimeMethod
safety and tolerability of Ripasudil in comparison with TimololTimepoint: day 14, 1 month, 2 months and 3 months
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