confirmatory trial to evaluate safety and efficacy of minimally invasive radiofrequency ablation therapy for primary aldosteronism patients (investigator-initiated clinical trial) - confirmatory trial of radiofrequency ablation therapy for primary aldosteronism patients

Department of Diagnostic Radiology,Tohoku University Hospital0 个研究点目标入组 38 人开始时间: 2014年12月8日最近更新: 2023年10月17日

试验速览

暂无简介。

•1. Pasemaker or ICD implantation 2. Possibilities of malignancy 3. impaired blood clotting with PT-INR>=2.0 4. Possibilities of infection 5. Intolerance to acute blood pressure change: a. Abdominal aortic aneurysm with diameter of more than 4cm, Thoracic aortic aneurysm with diameter of more than 5cm, Aortic dissection, Cerebral aneurysm >=5mm b. Impared cardiac function: Transthoracic US: LVEF<40% or E/E'>15 or BNP>200 pg/mL c. hypertensive intracranial bleeding without confirmation of hemostasis (should be confirmed by CT for cerebral bleeding within 180 days) 6.Cushing syndrome or paraganglioma 7. Pregnancy or possibility of pregnancy 8. Hystory of iodine allergy 9. Participants of other clinical trial 10. Difficulty in cessation of the drugs which are prohibited in this trial 11. Patients who are judged as in adequate for this trial by the investigators.

发起方

Department of Diagnostic Radiology,Tohoku University Hospital