Multimodal Imaging of Brain Activity to Investigate Walking and Mobility Decline in Older Adults
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Effect of Age-related Changes in the Brain on Walking Ability
- Sponsor
- University of Florida
- Enrollment
- 279
- Locations
- 1
- Primary Endpoint
- Brain activity during walking
- Status
- Completed
- Last Updated
- 9 months ago
Overview
Brief Summary
The objective of this study is to determine the central neural control of mobility in older adults by acquiring data with multiple modalities of neuroimaging (EEG, fNIRS, MRI) and associating these data with a comprehensive set of diverse mobility outcomes (clinic-based walking, complex walking and community mobility measures).
Detailed Description
This study is a longitudinal, prospective cohort study with a follow-up period of 1.2 - 3.5 years, dependent on when the participant enrolls. Participants will be assessed at baseline, and then every six months for 3.5 years or until the study ends, whichever comes first. The investigators plan to enroll 200 community-dwelling men and women age 70+ years.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Brain activity during walking
Time Frame: Baseline up to 42 months
Changes in brain activity during complex walking (uneven terrain), assessed longitudinally for up to 3.5 years