Glassy Trial for Effects of Wearing Glasses
- Conditions
- COVID-19
- Interventions
- Other: Overall uncertainty language
- Registration Number
- NCT05642754
- Lead Sponsor
- Trustees of Dartmouth College
- Brief Summary
Randomized trial testing 6 forms of a communication summarizing the results of a recent study (about the effects of wearing glasses on reducing covid infection risk).
The goal of the trial is to test the effect of different language options to describe uncertainty, and of including the margin of error around the main result.
- Detailed Description
The study is designed as a proof-of-concept exercise to develop and test a communication meant to summarize the results of a recent randomized trial examining the effects of wearing glasses on the chance of developing COVID-19.
The objectives of the randomized trial are:
* To compare the effects of three ways of communicating the overall uncertainty of the effects of wearing glasses to reduce the chance of getting COVID and
* To compare the effects of including the margin of error (confidence interval) compared to not including it.
Researchers will conduct an online, parallel group, individually randomized, pragmatic trial using a 3x2 factorial design, ie, 3 uncertainly language options (GRADE language, colloquial language or none 2 options for the statistical margin of error for the main results (margin of error language or none).
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 960
- >= 18 years old
- literate in English or Norwegian
- currently residing in Norway or the United States
- individuals who regularly wear any kind of glasses (i.e., prescription or sunglasses) all or most of the time
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- FACTORIAL
- Arm && Interventions
Group Intervention Description Colloquial language AND margin of error Overall uncertainty language Colloquial language developed to describe overall study uncertainty AND margin of error around main result GRADE -No margin of error Overall uncertainty language Overall uncertainty using GRADE\* language and NO margin of error around main result \* Based on the Cochrane Effective Practice and Organisation of Care Group's guidance for communicating the certainty of evidence based on the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach to assessing the certainty of evidence No overall uncertainty language AND no margin of error Overall uncertainty language No overall uncertainty language and NO margin of error around main result GRADE + margin of error Overall uncertainty language Overall uncertainty using GRADE\* language AND margin of error around main result \* Based on the Cochrane Effective Practice and Organisation of Care Group's guidance for communicating the certainty of evidence based on the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach to assessing the certainty of evidence No overall uncertainty language AND margin of error Overall uncertainty language No overall uncertainty language AND margin of error around main result Colloquial - No margin of error Overall uncertainty language Colloquial language developed to describe overall study uncertainty and NO margin of error around main result
- Primary Outcome Measures
Name Time Method understanding of overall uncertainty of harm (of wearing glasses to reduce the chance of covid infection) within 1 day How sure about the effect (4 point scale from very unsure to very sure)
understanding of overall uncertainty of benefit (of wearing glasses to reduce the chance of covid infection) within 1 day How sure about the effect (4 point scale from very unsure to very sure)
sufficiency of what is known about the effects of wearing glasses to reduce the chance of covid infection within 1 day How sure about the effect (4 point Likert scale)
Understanding the margin of error around the benefit of wearing glasses to reduce covid within 1 day this is a co-primary outcome which will be used only to compare the 3 versions that include the margin of error to the 3 versions that do not
- Secondary Outcome Measures
Name Time Method perceptions fo information provided (clarity of info about benefit) within 1 day 4 point scale (very clear, clear, unclear, very unclear)
perceptions fo information provided (info helpful?) within 1 day 4 point scale (very helpful, helpful, unhelpful, very unhelpful)
how likely is it that wearing glasses reduces the chance of covid infection within 1 day 4 point scale (very likely, likely, unlikely, very unlikely)
perceptions fo information provided (share info with others?) within 1 day 4 point scale (definitely yes, probably yes, probably no, definitely no)
Decisional conflict (hard to make decision) within 1 day 4 point LIkert scale (strongly agree, agree, disagree, strongly disagree)
intended behavior (if there were very few cases of covid in your area, how likely would you be to wear glasses to reduce the chance of covid infection within 1 day 4 point scale (very likely, likely, unlikely, very unlikely
perceptions fo information provided (sufficient summary?) within 1 day 4 point Likert scale (strongly agree, agree, disagree, strongly disagree)
perceptions fo information provided (clarity of info about harm) within 1 day 4 point scale (very clear, clear, unclear, very unclear)
perceived effect of wearing glasses to reduce chance of covid infection within 1 day What is the effect on a 5 point scale (lowers a lot, lowers a little, no effect, increase a little, increases a lot
intended behavior (if there were a surge in covid in your area, how likely would you be to wear glasses to reduce the chance of covid infection within 1 day 4 point scale (very likely, likely, unlikely, very unlikely
perceptions fo information provided (trustworthy summary?) within 1 day 4 point Likert scale (strongly agree, agree, disagree, strongly disagree)
Decisional conflict (made informed decision) within 1 day 4 point LIkert scale (strongly agree, agree, disagree, strongly disagree)
Decisional conflict (satisfied with decision) within 1 day 4 point LIkert scale (strongly agree, agree, disagree, strongly disagree)
Trial Locations
- Locations (1)
Norwegian Institute of Public Health
🇳🇴Oslo, Norway