Effect of orally given pregabalin before knee joint replacement on incidence of bandage induced reperfusion injury
Completed
- Conditions
- knee arhroplastyischemia-reperfusion injury
- Registration Number
- ACTRN12617001207303
- Lead Sponsor
- Baskent University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 54
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
How does pregabalin modulate molecular pathways to reduce tourniquet-induced ischemia-reperfusion injury in knee arthroplasty?
What comparative effectiveness data exist for pregabalin versus standard-of-care analgesics in mitigating tourniquet-induced ischemia-reperfusion injury?
What are the primary clinical endpoints in ACTRN12617001207303 regarding pregabalin's effect on tourniquet-induced ischemia-reperfusion injury?
Which biomarkers correlate with reduced oxidative stress or inflammation following pregabalin preadministration in knee arthroplasty patients?
Are gabapentinoids or antioxidants more effective in mitigating ischemia-reperfusion injury during total knee arthroplasty?