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临床试验/ISRCTN18221837
ISRCTN18221837已完成未知

Mechanisms of muscle wasting in advanced chronic kidney disease

niversity Hospitals of Leicester (UK)0 个研究点目标入组 73 人开始时间: 2016年2月10日最近更新:
适应症

试验速览

阶段
未知
状态
已完成
发起方
入组人数
73

研究概览

简要总结

2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35090033/ (added 18/09/2023) 2019 Results article in https://pubmed.ncbi.nlm.nih.gov/31914685/ (added 18/09/2023) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35029054/ (added 18/09/2023)

研究设计

研究类型
Observational

入排标准

性别
All

入选标准

  • CKD patients:
  • 1. Over 18 years of age
  • 2. Diagnosed CKD stage 3b-5
  • 3. If diabetic, good control - HbA1c <9%
  • Matched controls - will be matched to CKD patients for age, sex and race.
  • 1. Over 18 years of age
  • 2. Kidney function < 80mL/min/1.73m2
  • 3. Good general health

排除标准

  • CKD patients:
  • 1. Aged under 18 years
  • 2. Uncontrolled diabetes mellitus (HbA1c >9%)
  • 3. Inability to give consent for any reason
  • Matched controls:
  • 1. Aged under 18 years
  • 2. Presence of CKD (eGFR>80mL/min/1.73m2)
  • 3. Presence of other diseases known to cause muscle wasting (some cancers, sepsis, burns and HIV)
  • 4. Inability to give informed consent for any reason.

研究者

发起方
niversity Hospitals of Leicester (UK)

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