Intrathecal ropivacaine vs bupivacaine in endoscopic urological surgeries
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 142
- 试验地点
- 1
- 主要终点
- Onset of sensory block, onset and duration of motor block, highest level of sensory block
研究概览
简要总结
The aim of our study is to compare the clinical effect of 0.75% intrathecal isobaric ropivacaine with 0.5% intrathecal hyperbaric bupivacaine. Group 1 patients received 3 ml of hyperbaric bupivacaine and Group 2 patients received 2 ml of 0.75% isobaric ropivacaine. Both the groups were compared for onset of sensory block, onset and duration of motor block, highest level of sensory block. There was no significant diffrence between the two groups in mean time to onset of sensory block at T10, 5.79+/- 1.38 minute with ropivacaine and 5.68+/-1.57 minute with bupivacaine. Highest level of sensory block attained was T6 in both groups. From the study we concluded that 2ml 0.75% ropivacaine provided comparable quality of sensory block but had slower onset and significantly shorter duration compared to 3ml 0.5% bupivacaine
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA 1, 2& 3 scheduled for urological surgery under spinal anaesthesia.
排除标准
- •1.Patients with contraindication to spinal anaesthesia 2.patient with history of allergy to amide local anaesthetics.
结局指标
主要结局
Onset of sensory block, onset and duration of motor block, highest level of sensory block
时间窗: After intrathecal injection of drug to end of procedure
次要结局
- Quality of anaesthesia and muscle relaxation, haemodynamic parameters and adverse effects if any were studied(After intrathecal injection of drug to end of procedure)