CTRI/2026/01/100301尚未招募2 期
A randomized clinical study of the effects of early use of Methylene Blue on Noradrenaline dose in shock.
Subharti Medical College1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2026年1月26日最近更新:
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- CHANGE IN NORAD DOSE AFTER STARTING VASOPRESSIN AND METHYLENE BLUE
研究概览
简要总结
THIS STUDY IS A RANDOMIZED CLINICAL STUDY OF THE EFFECTS OF EARLY USE OF METHYLENE BLUE ON NORADRENALINE DOSE IN SHOCK WHERE THERE WILL BE A COMPARISON BETWEEN TWO GROUPS WHERE ONE WILL RECEIVE ONLY VASO AND ANOTHER VASO+ METHYLENE BLUE AFTER A CERTAIN DOSE OF NORAD.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)（—）
- 性别
- All
入选标准
- •Patient admitted in ICU with shock and requires noradrenaline to maintain a mean arterial pressure (MAP) of greater than or equal to 65 mm Hg after appropriate fluid resuscitation.
排除标准
- •relatives/patient refused to provide consent With unstable coronary artery syndrome, stroke chronic renal failure requiring dialysis, malignancy or irreversible illness with a high mortality risk, acute mesenteric ischemia, pregnancy known hypersensitivity to norepinephrine or Methylene Blue or Vasopressin Glucose-6-phosphate dehydrogenase (G6PD) deficiency.
结局指标
主要结局
CHANGE IN NORAD DOSE AFTER STARTING VASOPRESSIN AND METHYLENE BLUE
时间窗: 0 hours, 6 hours, 12 hours, 24 hours
次要结局
- Changes in Lactate Levels,(Urine Output)
研究者
Akshita
Subharti medical college
研究点 (1)
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