Immunogenicity and Thrombotic Potential of Circulating Protamine-heparin Complexes in Cardiac Surgery Patients

Completed

• Conditions: Thrombocytopenia; Antibodies Drug Specific

• Registration Number: NCT06565364
• Lead Sponsor: Medical University of Vienna

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-8-7
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 160

Inclusion Criteria

Inclusion Criteria:<br><br> - age = 18 years<br><br> - cardiac surgery on cardiopulmonary bypass<br><br>Exclusion Criteria:<br><br> - cardiac surgery without cardiopulmonary bypass<br><br> - age < 18 years<br><br> - no written consent

Exclusion Criteria

Not provided

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
prevalence of protamine/heparin antibodies

Secondary Outcome Measures

Name	Time	Method
Potential triggers;Clinical impact