DRKS00000735招募中不适用
eurological sequelae and changes in nociception after severe sepsis or septic shock - NeuroPain
Integriertes Forschungs- und Behandlungszentrum (IFB) Sepsis und Sepsisfolgen: Center for Sepsis Control and Care (CSCC); Universitätsklinikum Jena0 个研究点目标入组 120 人开始时间: 2011年3月21日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 120
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 85 Years（—）
- 性别
- All
入选标准
- •Common inclusion criteria (all participants):
- •Minimum age: 18; informed consent, sufficient skills in German language;
- •Sepsis specific: Maximum age: 85, survivors of severe sepsis/ septic shock; duration of mechanical ventilation = 3 days in ICU;
- •non septic ICU patients: Maximum age: 85;duration of mechanical ventilation = 3 days in ICU;
- •HE sepcific: Maximum age: 65; confirmed diagnosis of liver failure (sonographic, CT, histological); HE-grade 0-2,
- •Control specific: Maximum Age for neurological examinations: 65 and 85 years for pain examinations
排除标准
- •common exclusion criteria (for all participants):
- •Participation in a different study; confirmed diagnosis of dementia or other severe neurological disorder (epilepsy included); seizure, confirmed septic shock or severe sepsis in anamnesis; recent drug abuse and/ or alcohol intoxication
- •sepsis specific: medication with analgetics; Amputation of upper limbs; confirmed chronic or other neuropathic pain disorder;
- •additionally for neurological examinations (25 patients): Medication with neuroleptics, sedatives, antidepressants, Amaurosis
- •non-septic ICU patients: ICU stay due to sepsis or septic shock; medication with analgetics; Amputation of upper limbs; confirmed chronic or other neuropathic pain disorder;
- •HE-specific: Medication with neuroleptics, sedatives, antidepressants, Amaurosis; life expectancy < 1 year; spontaneous bacterial peritonitis; actual delir and/ or deprivation; liver transplantation
- •control specific: medication with analgetics, amputation of the upper limbs; confirmed confirmed chronic or other neuropathic pain disorder; medication with neuroleptics, sedatives, antidepressants, Amaurosis;
- •MEG and MRI-sepcific: pace maker and other magnetic implants; claustrophobics; pregnancy
研究者
相似试验
尚未招募
不适用
Impact of nociceptive Stimuli on Parameters of narcosis, the peripheral Plethysmography (SPI) und the electrocardiogram (ANI) on elderly patients over 80 years old in General anesthisia.Monitoring advices of algesimetryDRKS00011086Klinik für Anästhesie und operative Intensivmedizin, UKSH Kiel44
已完成
不适用
Characterization of nociceptive perturbation and threshold tracking methodsNL-OMON39755MIRA Institute for Biomedical Technology and Technical Medicine, University of Twente165
尚未招募
3 期
Investigation into the Acute and Chronic Effects of Longvida Curcumin on Cognitive Function, Mood and Biomarkers of Health in an Elderly Population.Cognitive functionCerebral Blood Flow (fMRI)InflamationOxidative stressMood, stress and fatigueMental Health - Studies of normal psychology, cognitive function and behaviourAlternative and Complementary Medicine - Herbal remediesACTRN12612001027808Swinburne University of Technology, Centre for Human Psychopharmacology60
招募中
3 期
morphine plus Naloxone in cesariaIRCT20140524017811N8Sari University of Medical Sciences60
已完成
不适用
Effects of monitoring of nociceptive levels during general anesthesia on postoperative complicationsAbdominal tumors and inflammatory diseasesJPRN-UMIN000035415Hyogo Medical University100