The Effectiveness of Astaxanthin plus F. on facial skin quality

Phase 1

• Conditions: Healthy women; Astraxanthin; natural oil; vitamin E; vitamin D3; facial skin

• Registration Number: TCTR20210301005
• Lead Sponsor: Prevent U company limited

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-03-01
• Study Completion: 2021-04-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending (Not yet recruiting)
• Sex: Female
• Target Recruitment: 42

Inclusion Criteria

1. female
2. age 35-45 years
3. General good health and mental condition , no evidence of underlying disease
4. regular menstrual cycles
5. Person who agrees to participate in the study and has affixed her signature in the written consent to participate in the study.
6. Person without history of Carotenoids and Astaxanthin hypersensitivity
7. Person without skin diseases, eczema and inflammation at the areas to be measured.
8. Person who had not received any medical operation for skin treatment on the areas to be measured such as exfoliation, iontophoresis and radiofrequency within one month prior to participating in the study.
9. Person who had not injected with Botulinum toxin at the areas to be measured within 8 months prior to participating in the study.
10. Person who had not injected with any fillers at the areas to be measured within 1 year prior to participating in the study.
11. Non-smoker
12. Person who does not live a lifestyle that is exposed to intense heat and sunlight for many hours a day without protection.
13. Person who is not pregnant or breastfeeding

Exclusion Criteria

1. Expressing their intention to drop out or have reasons to drop out.
2. Became pregnant during the study period.
3. Experiencing adverse reactions, side effects or allergic reactions while taking the supplement tested.
4. Forgetting to take any supplement or placebo given for more than 2 consecutive days or more 2 days a week or more than 4 days a month.
5. Undergoing any medical procedure such as Botulinum toxin injection, filler injection, and laser treatment during the test.
6. Changes in skin and health care behaviors during the study period such as taking other drugs or dietary supplements, applying additional moisturizer or cream or stopping the skin care routine during the test.
7. Experiencing skin disease, allergic rash, severe inflammation at the measured areas.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
skin elasticity at 8 weeks after the intervention cutometer dual MPA580,skin hydration at 8 weeks after the intervention cutometer dual MPA580 ( corneometer ),transepidermal water loss at 8 weeks after the intervention cutometer dual MPA580 ( tewameter ),pigmentation at 8 weeks after the intervention cutometer dual MPA580 ( mexameter ),wrinkles at 8 weeks after the intervention VISIA 7th generation

Secondary Outcome Measures

Name	Time	Method
/A N/A N/A