Acute Nutritional Ketosis in VLCAD Deficiency: testing the metabolic basis for therapeutic use - Acute Nutritional Ketosis in VLCADD

niversitair Medisch Centrum Groningen0 个研究点目标入组 6 人开始时间: 待定最近更新: 2024年4月23日

适应症

试验速览

暂无简介。

•* contra indications for MRI studies (assessed by standardised questionnaire as previously used in METc 08-267/K. Such as metal implants, vascular clips, eye-implants, metal particles in the eye, tattoos containing iron oxide, suspected pregnancy, refusal to be informed of strucural brain abnormalities that could be detected)
•* inability to perform bicycle exercise.
•* recent episode of rhabdomyolysis, or treatment for acute renal failure in the past 2
•* intercurrent illness which may influence exercise tolerance (anaemia, musculoskeletal
•injury, or other undiagnosed illness under investigation).
•* known coronary artery disease, positive history for angina, or changes on ECG
•suggestive of previous ischaemia without a negative stress test.
•* insulin-dependent diabetes mellitus.
•* loss of, or an inability to give informed consent.
•* pregnancy or current breastfeeding, or females not taking the oral contraceptive pill
•* any other cause which in the opinion of the investigators, may affect the volunteers
•ability to participate in the study

发起方