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临床试验/CTRI/2026/04/107398
CTRI/2026/04/107398尚未招募不适用

Association of phthalates with primary ovarian cancer

Maulana Azad Medical College1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2026年4月6日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
80
试验地点
1

研究概览

简要总结

This study aims to assess whether exposure to phthalates, commonly used plasticizers, is associated with primary ovarian cancer. Urinary levels of di(2-ethylhexyl) phthalate (DEHP) and its metabolite will be compared between women with ovarian cancer and age-matched healthy women. Laboratory studies will also evaluate the effects of these chemicals on ovarian cancer cell growth and migration. The study will be conducted after ethics approval and informed consent at Maulana Azad Medical College and associated hospitals.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 99.00 Year(s)(—)
性别
Female

入选标准

  • For Cases: Females with radiologically and biochemically proven primary ovarian cancer scheduled for surgery, with diagnosis to be subsequently confirmed by histopathological examination.
  • For Controls: Apparently age matched healthy females, mainly attendants of the patients.

排除标准

  • Presence of chronic illness
  • Patients living in areas with occupational hazards
  • Pregnant and lactating females
  • Females currently undergoing cancer treatment
  • Females diagnosed with other malignancies
  • Female with hormone-dependent conditions.

研究者

申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Dr Begum Jazia A

Maulana Azad Medical College

研究点 (1)

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