Evaluation of the effect of stem cell-mediated gene therapy in the treatment of glioblastoma

Phase 2

Completed

• Conditions: Glioma grade 4.; Malignant neoplasm of cerebellum

• Registration Number: IRCT20200502047277N3
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2024-05-27

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Karnofsky performance status> 70.
Adequate hematological function (an absolute neutrophil count > 1500/µl and platelet count > 125000/mm3).
Adequate renal function (creatinine < 1.5 times the normal).
Adequate hepatic function (aspartate aminotransferase and bilirubin < 1.5 times the normal).
Patient who fill informed consent.

Exclusion Criteria

Significant vascular disease.
History of recurrent thromboembolism.
Prior history of hypertensive crisis or hypertensive encephalopathy.
Gastrointestinal fistula or perforation.
History of intraabdominal or intracranial abscess within 6 months.
Serious non healing wound, ulcer and bone fracture.

Study & Design

• Study Type: interventional
• Study Design: Not specified